Evidence map›Paper›PMID 34507118›Full record

ReviewBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie2021

Recent progress in micro and nano-encapsulation of bioactive derivatives of the Brazilian genus Pterodon.

Janaina de Alcantara Lemos, Anna Eliza M F M Oliveira, Raquel Silva Araujo, Danyelle M Townsend, Lucas Antonio Miranda Ferreira, Andre Luis Branco de Barros

Abstract readReview
In one paragraph

Review in Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. ExtractedPlants (Basel, Switzerland) · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Janaina de Alcantara LemosDepartment of Pharmaceutical Products, Faculty of Pharmacy, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, Minas Gerais, Brazil.
Anna Eliza M F M OliveiraDepartment of Biological Sciences and Health, Universidade Federal do Amapá, 68903-329 Macapá, Amapá, Brazil.
Raquel Silva AraujoDepartment of Pharmacy, Pharmacy School, Universidade Federal de Ouro Preto, 35400-000 Ouro Preto, Minas Gerais, Brazil.
Danyelle M TownsendDepartment of Drug Discovery and Pharmaceutical Sciences, Medical University of South Carolina, USA.
Lucas Antonio Miranda FerreiraDepartment of Pharmaceutical Products, Faculty of Pharmacy, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, Minas Gerais, Brazil.
Andre Luis Branco de BarrosDepartment of Clinical and Toxicological Analysis, Faculty of Pharmacy, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, Minas Gerais, Brazil. Electronic address: brancodebarros@yahoo.com.br.

Funding

SOUTH CAROLINA COBRE IN OXIDANTS, REDOX BALANCE AND STRESS SIGNALINGP20GM103542 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI TEW, KENNETH D. · 2012 to 2020
$20.2M
South Carolina COBRE in Oxidants, Redox Balance and Stress SignalingP30GM140964 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI EBLEN, SCOTT T · 2021 to 2025
$6.4M
SOUTH CAROLINA COBRE IN OXIDANTS, REDOX BALANCE AND STRESS SIGNALINGP20RR024485 · NCRR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI TEW, KENNETH D. · 2011 to 2011
$2.2M
MUSC FACIL EXPANSION &RENOV: SLE C06RR015455 · NCRR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI CROUCH, ROSALIE K · 2002 to 2002
$2.0M
NCRR NIH HHS C06 RR015455NCRR NIH HHS P20 RR024485NIGMS NIH HHS P20 GM103542NIGMS NIH HHS P30 GM140964
6 · The paper itself

Abstract

In the last few decades, utilization of medicinal plants by the pharmaceutical industry has led to the identification of many new bioactive compounds. The genus Pterodon, native of the Brazilian Flora, is known for the therapeutic properties attributed to its species, which are widely used in popular medicine for their anti-inflammatory, anti-rheumatic, tonic, and depurative properties. The intrinsic low water solubility of the plant derivatives from the genus, including diterpenes with vouacapane skeletons that are partially associated with the pharmacological activities, impairs the bioavailability of these bioactive compounds. Recent studies have aimed to encapsulate Pterodon products to improve their water solubility, achieve stability, increase their efficacy, and allow clinical applications. The purpose of this paper is to review recent research on the use of nanotechnology for the development of new products from plant derivatives of the Pterodon genus in different types of micro- and nanocarriers. Therapeutic properties of their different products are also presented. Finally, an update about the current and future applications of encapsulated formulations is provided.

Indexed as

Drug CarriersFabaceaeNanoparticlesPlants, MedicinalAnimalsBrazilDrug CompoundingDrug LiberationDrug StabilityHumansNanotechnologyPhytochemicalsPlant ExtractsPlant OilsSolubilityDrug CarriersPhytochemicalsPlant ExtractsPlant OilsEncapsulationLipidic nanoparticleNatural productsPolymeric nanoparticlePterodonTerpenes

Identifiers

PMID34507118
PMCPMC8963538

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.