Non-steroidal anti-inflammatory drugs are not associated with increased risk of Clostridioides difficile infection: A propensity-score-matched case-control study.

Adam M Ressler, Alieysa Patel, Krishna Rao

Abstract read

In one paragraph

Article in Anaerobe, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Association between Pregestational Vaginal Dysbiosis and Incident Hypertensive Disorders of Pregnancy Risk: a Nested Case-Control Study.mSphere · 2023
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Adam M ResslerDivision of Infectious Diseases, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA. Electronic address: resslead@umich.edu.

Alieysa PatelDepartment of Pathology, University of Michigan, Ann Arbor, MI, USA.

Krishna RaoDivision of Infectious Diseases, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA. Electronic address: krirao@med.umich.edu.

Funding

Systems biology of Clostridium difficile infectionU01AI124255 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCHLOSS, PATRICK DAVID, YOUNG, VINCENT B · 2016 to 2020

$9.8M

NIAID NIH HHS U01 AI124255

6 · The paper itself

Abstract

Prior research identified an increased risk for Clostridioides difficile infection (CDI) following exposure to certain non-steroidal anti-inflammatory drugs (NSAIDs). We conducted a retrospective case-control study to evaluate the risk for CDI associated with NSAID use. NSAID use was not associated with an increased risk of CDI.

Indexed as

Disease SusceptibilityAgedAnti-Inflammatory Agents, Non-SteroidalCase-Control StudiesClostridiumClostridium InfectionsFemaleHumansMaleMiddle AgedOdds RatioPropensity ScorePublic Health SurveillanceRisk AssessmentRisk FactorsAnti-Inflammatory Agents, Non-SteroidalClostridioides difficileNSAIDPropensity scoreRisk factors

Identifiers

PMID34506930

DOI10.1016/j.anaerobe.2021.102444

PMCPMC8678209

What OpenQuestion holds

Textmetadata

LicenceTDM

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.