ArticleJournal of vascular surgery2022
Sex-specific criteria for repair should be utilized in patients undergoing aortic aneurysm repair.
Article in Journal of vascular surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 30 citations in OpenAlex.
- Circulating tumor DNA mediates the effect of intrapleural cisplatin retention on non-small cell lung cancer malignant pleural effusion.American journal of translational research · 2026Article
- Anatomical analysis of the abdominal aorta in a South African sample: influence of age and sex.Surgical and radiologic anatomy : SRA · 2024Article
- The relationship of sex and aortic diameter at the time of acute type A aortic dissection.JTCVS open · 2024Article
- Higher small pulmonary artery and vein volume on computed tomography is associated with mortality in current and former smokers.EBioMedicine · 2024Article
- The association of ruptured abdominal aortic aneurysm diameter with mortality in the International Consortium of Vascular Registries.Journal of vascular surgery · 2024Article
- Female-Specific Considerations in Aortic Health and Disease.CJC open · 2024Review
- Association of women-specific size threshold and mortality in elective abdominal aortic aneurysm repair.The British journal of surgery · 2024Article
- Prevalence of abdominal aortic aneurysm (AAA) in first-degree relatives: detecting AAA in adult offspring of AAA patients.BJS open · 2024Article
- Cross-sectional, multicenter study comparing sex differences in patients undergoing endovascular repair of infrarenal abdominal aortic aneurysms. Results from the São Paulo State University Provincial Hospitals Registry (RHEUNI).Jornal vascular brasileiro · 2024Article
- Clinical presentation, outcomes, and threshold for repair by sex in degenerative saccular vs fusiform aneurysms in the descending thoracic aorta.Journal of vascular surgery · 2023Article
- Systematic Review and Meta-Analysis of the Incidence of Rupture, Repair, and Death of Small and Large Abdominal Aortic Aneurysms under Surveillance.Journal of clinical medicine · 2023Review
- Sex-Related Differences in Proximal Neck Anatomy and Their Consequences in Patients after EVAR: A Matched Cohort Analysis.Journal of clinical medicine · 2023Article
- Disparities in reporting and representation by sex, race, and ethnicity in endovascular aortic device trials.Journal of vascular surgery · 2022Article
- Disparities in 5-year outcomes and imaging surveillance following elective endovascular repair of abdominal aortic aneurysm by sex, race, and ethnicity.Journal of vascular surgery · 2022Article
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
Abstract
objectiveFemale patients are more likely to undergo repair of intact and ruptured abdominal aortic aneurysm (AAA) at smaller aortic diameter compared with male patients. By adjusting for inherent anatomic differences between sexes, aortic size index (ASI) and aortic height index (AHI) may provide an additional method for guiding treatment. We therefore analyzed sex-specific criteria for AAA repair using aortic diameter, ASI, and AHI.
methodsWe identified all patients who underwent AAA repair between 2003 and 2019 in the Vascular Quality Initiative database. The Dubois and Dubois formula was used to calculate body surface area; aortic diameter was divided by body surface area to calculate ASI. Aortic diameter was divided by height to calculate AHI. Cumulative distribution curves were used to plot the proportion of patients who underwent repair of ruptured aneurysm according to aortic diameter, ASI, and AHI. Multivariable logistic regression modeling was used to identify the association of female sex with perioperative mortality and any major postoperative complication.
resultsWe identified 55,647 patients, of whom 12,664 were female (20%). For both intact and rupture repair, female patients were older, less likely to undergo endovascular aneurysm repair, and more likely to have comorbid conditions. Female patients underwent repair at smaller median aortic diameter compared with male patients for intact (5.4 vs 5.5 cm; P < .001) and rupture repair (6.7 vs 7.7 cm; P < .001). However, ASI was higher in female patients for both intact (3.1 vs 2.7 cm/m
conclusionsOur study provides data to strongly support the sex-specific 5.0-cm aortic diameter threshold suggested for repair in female patients by the Society for Vascular Surgery. The high percentage of patients undergoing rupture repair below 5.5 cm in male patients and 5.0 cm in female patients highlights the need to better identify patients at risk of rupture at smaller aortic diameters.
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