ReviewNeuroscience2022
Active Dendrites and Local Field Potentials: Biophysical Mechanisms and Computational Explorations.
Review in Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 36 citations in OpenAlex.
- Loss of Fmr1 causes subnucleus-specific decreases in dendritic complexity in mediodorsal thalamus.Brain structure & function · 2026Article
- Therapeutic Targets and Signaling Mechanisms in 2D and 3D In Vitro Models of Osteoarthritis.Clinical anatomy (New York, N.Y.) · 2026Review
- Dichotomy between extracellular signatures of active dendritic chemical synapses and gap junctions.eLife · 2026Article
- Acute and Chronic Local Field Potential Recordings in Dystonia-A Systematic Review.Movement disorders clinical practice · 2026Review
- Temporal-Spatial Fusion Vision Hardware Enables Streamlined In-Sensor Computing for Dynamic Scenes.Nature communications · 2026Article
- Direct laser carbonization of parylene-C toward microelectrodes forFrontiers in neuroscience · 2026Article
- Degeneracy Explains Diversity in Interneuronal Regulation of Pattern Separation in Heterogeneous Dentate Gyrus Networks.Function (Oxford, England) · 2025Article
- Cortical dynamics of neural-connectivity fields.Journal of computational neuroscience · 2025Article
- B(RAIN)Scientific data · 2025Article
- Review
- A concise mathematical description of signal transformations across the hippocampal apical CA3 to CA1 dendritic response.Frontiers in neural circuits · 2025Article
- Cross-strata co-occurrence of ripples with theta-frequency oscillations in the hippocampus of foraging rats.The Journal of physiology · 2024Article
- Bioelectronic Medicine: a multidisciplinary roadmap from biophysics to precision therapies.Frontiers in integrative neuroscience · 2024Review
- Dynorphin / kappa-opioid receptor regulation of excitation-inhibition balance toggles afferent control of prefrontal cortical circuits in a pathway-specific manner.Molecular psychiatry · 2023Article
- Increased noise relates to abnormal excitation-inhibition balance in schizophrenia: a combined empirical and computational study.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Ion-channel degeneracy and heterogeneities in the emergence of complex spike bursts in CA3 pyramidal neurons.The Journal of physiology · 2023Article
- Spatial learning impairments and discoordination of entorhinal-hippocampal circuit coding following prolonged febrile seizures.Hippocampus · 2023Article
- Article
- A Dynamical Systems Approach to Characterizing Brain-Body Interactions during Movement: Challenges, Interpretations, and Recommendations.Sensors (Basel, Switzerland) · 2023Review
- Degeneracy in epilepsy: multiple routes to hyperexcitable brain circuits and their repair.Communications biology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Neurons and glial cells are endowed with membranes that express a rich repertoire of ion channels, transporters, and receptors. The constant flux of ions across the neuronal and glial membranes results in voltage fluctuations that can be recorded from the extracellular matrix. The high frequency components of this voltage signal contain information about the spiking activity, reflecting the output from the neurons surrounding the recording location. The low frequency components of the signal, referred to as the local field potential (LFP), have been traditionally thought to provide information about the synaptic inputs that impinge on the large dendritic trees of various neurons. In this review, we discuss recent computational and experimental studies pointing to a critical role of several active dendritic mechanisms that can influence the genesis and the location-dependent spectro-temporal dynamics of LFPs, spanning different brain regions. We strongly emphasize the need to account for the several fast and slow dendritic events and associated active mechanisms - including gradients in their expression profiles, inter- and intra-cellular spatio-temporal interactions spanning neurons and glia, heterogeneities and degeneracy across scales, neuromodulatory influences, and activitydependent plasticity - towards gaining important insights about the origins of LFP under different behavioral states in health and disease. We provide simple but essential guidelines on how to model LFPs taking into account these dendritic mechanisms, with detailed methodology on how to account for various heterogeneities and electrophysiological properties of neurons and synapses while studying LFPs.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.