Evidence map›Paper›PMID 34506551›Full record

ArticlePloS one2021

Examining and investigating the impact of demographic characteristics and chronic diseases on mortality of COVID-19: Retrospective study.

Abbas Al Mutair, Alya Al Mutairi, Saad Alhumaid, Syed Maaz Abdullah, Abdul Rehman Zia Zaidi, Ali A Rabaan, Awad Al-Omari

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 3 countries.

Abbas Al MutairResearch Center Director, Almoosa Specialist Hospital, Al-Ahsa, Saudi Arabia.
Alya Al MutairiMathematics Department, Taibah University, Medina, Saudi Arabia.ORCID 0000-0003-4181-6279
Saad AlhumaidDrug Information and Research Department, Administration of Pharmaceutical Care, Ministry of Health, Al-Ahsa, Saudi Arabia.
Syed Maaz AbdullahDepartment of Medicine, King Edward Medical University, Lahore, Pakistan.
Abdul Rehman Zia ZaidiResearch Center, Dr. Sulaiman Al Habib Medical Group, Riyadh, Saudi Arabia.
Ali A RabaanMolecular Diagnostics Laboratory, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.
Awad Al-OmariResearch Center, Dr. Sulaiman Al Habib Medical Group, Riyadh, Saudi Arabia.
Alfaisal University · SAKing Edward Medical University · PKMinistry of Health · SAPrincess Nourah bint Abdulrahman University · SASaudi Aramco Medical Services Organization · SASulaiman Al Rajhi Colleges · SATaibah University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEpidemiological features characterization of COVID-19 is highly important for developing and implementing effective control measures. In Saudi Arabia mortality rate varies between 0.6% to 1.26%. The purpose of the study was to investigate whether demographic characteristics (age and gender) and non-communicable diseases (Hypertension and Diabetes mellitus) have a significant association with mortality in COVID-19 patients.

methodsPrior to data collection, an expedite approval was obtained from Institutional Review Board (IRB Log No: RC. RC20.09.10) in Al Habib Research Center at Dr. Sulaiman Al-Habib Medical Group, Riyadh, Saudi Arabia. This is a retrospective design where we used descriptive and inferential analysis to analyse the data. Binary logistic regression was done to study the association between comorbidities and mortality of COVID-19.

results43 (86%) of the male patients were non-survivors while 7 (14%) of the female patients were survivors. The odds of non-survivors among hypertensive patients are 3.56 times higher than those who are not having a history of Hypertension (HTN). The odds of non-survivors among diabetic patients are 5.17 times higher than those who are not having a history of Diabetes mellitus (DM). The odds of non-survivors are 2.77 times higher among those who have a history of HTN and DM as compared to those who did not have a history of HTN and DM.

conclusionsThose patients that had a history of Hypertension and Diabetes had a higher probability of non-survival in contrast to those who did not have a history of Diabetes and hypertension. Further studies are required to study the association of comorbidities with COVID-19 and mortality.

Indexed as

AdolescentAdultAge FactorsChildChronic DiseaseComorbidityCOVID-19Diabetes MellitusFemaleHumansHypertensionMaleMiddle AgedRetrospective StudiesRisk FactorsSaudi Arabia

Identifiers

PMID34506551
PMCPMC8432755
OpenAlexW3134499503

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.