Evidence map›Paper›PMID 34506225›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2021

Ahmed Aboulgheit, Catherine Karbasiafshar, Zhiqi Zhang, Mohamed Sabra, Guangbin Shi, Aja Tucker, Neel Sodha, M Ruhul Abid, Frank W Sellke

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Nutrients · 2025
    Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Potential effects of probiotics on atherosclerosis.Microbiome research reports · 2025
    Review
  16. Review
  17. Review
  18. Antioxidant Role of Probiotics in Inflammation-Induced Colorectal Cancer.International journal of molecular sciences · 2024
    Review
  19. The gut microbiome as a modulator of arterial function and age-related arterial dysfunction.American journal of physiology. Heart and circulatory physiology · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ahmed AboulgheitDivision of Cardiothoracic Surgery, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, Rhode Island.ORCID 0000-0003-1900-7619
Catherine KarbasiafsharDivision of Cardiothoracic Surgery, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, Rhode Island.
Zhiqi ZhangDivision of Cardiothoracic Surgery, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, Rhode Island.
Mohamed SabraDivision of Cardiothoracic Surgery, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, Rhode Island.ORCID 0000-0001-8336-9783
Guangbin ShiDivision of Cardiothoracic Surgery, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, Rhode Island.
Aja TuckerDivision of Cardiothoracic Surgery, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, Rhode Island.
Neel SodhaDivision of Cardiothoracic Surgery, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, Rhode Island.
M Ruhul AbidDivision of Cardiothoracic Surgery, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, Rhode Island.ORCID 0000-0003-2981-2638
Frank W SellkeDivision of Cardiothoracic Surgery, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, Rhode Island.ORCID 0000-0002-8886-801X
Brown University · US

Funding

Uncoupling of IL-1 beta and VEGF-A Crosstalk Contributes to Impaired Arteriogenesis Response to Ischemia in Chronic Diabetes MellitusP20GM103652 · NIGMS · OCEAN STATE RESEARCH INSTITUTE, INC. · PI CHOUDHARY, GAURAV, HARRINGTON, ELIZABETH O · 2013 to 2022
$21.3M
Effect of Cardioplegia and Cardiopulmonary Bypass on Coronary Microvascular ReactivityR01HL046716 · NHLBI · RHODE ISLAND HOSPITAL · PI SELLKE, FRANK W · 1997 to 2023
$8.5M
Vascular Dysfunction in Myocardial Ischemia and Metabolic SyndromeR01HL128831 · NHLBI · RHODE ISLAND HOSPITAL · PI SELLKE, FRANK W, USHEVA-SIMIDJIYSKA, ANNY · 2016 to 2025
$5.7M
Short-Term Training Program to Increase Diversity in Health-Related ResearchR25HL088992 · NHLBI · BROWN UNIVERSITY · PI ABID, RUHUL, DIAZ, JOSEPH A · 2007 to 2024
$1.9M
Sub-cellular Targeting of Endothelial ROS in Myocardial IschemiaR01HL133624 · NHLBI · RHODE ISLAND HOSPITAL · PI ABID, RUHUL · 2017 to 2020
$1.6M
Cardiovascular Surgery Research TrainingT32HL160517 · NHLBI · RHODE ISLAND HOSPITAL · PI Frank W Sellke · 2022 to 2026
$1.5M
NHLBI NIH HHS R01 HL046716NHLBI NIH HHS R01 HL128831NHLBI NIH HHS R01 HL133624NHLBI NIH HHS R25 HL088992NHLBI NIH HHS T32 HL160517NIGMS NIH HHS P20 GM103652
6 · The paper itself

Abstract

Yorkshire swine were fed standard diet (

Indexed as

ProbioticsVentricular Function, LeftAnimal FeedAnimalsCoronary CirculationDiastoleDisease Models, AnimalEndothelial CellsFemaleFibrosisHeme Oxygenase-1Lactiplantibacillus plantarumMaleMicrovascular DensityMyocardial IschemiaMyocardiumHeme Oxygenase-1NAD(P)H Dehydrogenase (Quinone)NF-E2-Related Factor 2Nitric Oxide Synthase Type IIIThioredoxinsantioxidantchronic myocardial ischemiadiastolic functionendothelial functionprobiotic

Identifiers

PMID34506225
PMCPMC8616611
OpenAlexW3197348604

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.