Evidence map›Paper›PMID 34505958›Full record

ArticleJournal of digital imaging2021

MR Denoising Increases Radiomic Biomarker Precision and Reproducibility in Oncologic Imaging.

Matías Fernández Patón, Leonor Cerdá Alberich, Cinta Sangüesa Nebot, Blanca Martínez de Las Heras, Diana Veiga Canuto, Adela Cañete Nieto, Luis Martí-Bonmatí

Abstract read
In one paragraph

Article in Journal of digital imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Pancreatic cancer, radiomics and artificial intelligence.The British journal of radiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Matías Fernández PatónGrupo de Investigación Biomédica en Imagen, Instituto de Investigación Sanitaria La Fe, Avenida Fernando Abril Martorell, 106 Torre A 7planta, 46026, Valencia, Spain. matias_fernandez@iislafe.es.ORCID 0000-0001-9374-1411
Leonor Cerdá AlberichGrupo de Investigación Biomédica en Imagen, Instituto de Investigación Sanitaria La Fe, Avenida Fernando Abril Martorell, 106 Torre A 7planta, 46026, Valencia, Spain.ORCID 0000-0002-5567-4278
Cinta Sangüesa NebotÁrea Clínica de Imagen Médica, Hospital Universitario Y Politécnico La Fe, Avenida Fernando Abril Martorell, 106, 46026, Valencia, Spain.ORCID 0000-0002-2939-3632
Blanca Martínez de Las HerasUnidad de Oncohematología Pediátrica, Hospital Universitario Y Politécnico La Fe, Avenida Fernando Abril Martorell, 106, 46026, Valencia, Spain.
Diana Veiga CanutoÁrea Clínica de Imagen Médica, Hospital Universitario Y Politécnico La Fe, Avenida Fernando Abril Martorell, 106, 46026, Valencia, Spain.ORCID 0000-0002-6048-2940
Adela Cañete NietoUnidad de Oncohematología Pediátrica, Hospital Universitario Y Politécnico La Fe, Avenida Fernando Abril Martorell, 106, 46026, Valencia, Spain.ORCID 0000-0002-5669-5097
Luis Martí-BonmatíGrupo de Investigación Biomédica en Imagen, Instituto de Investigación Sanitaria La Fe, Avenida Fernando Abril Martorell, 106 Torre A 7planta, 46026, Valencia, Spain.ORCID 0000-0002-8234-010X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several noise sources, such as the Johnson-Nyquist noise, affect MR images disturbing the visualization of structures and affecting the subsequent extraction of radiomic data. We evaluate the performance of 5 denoising filters (anisotropic diffusion filter (ADF), curvature flow filter (CFF), Gaussian filter (GF), non-local means filter (NLMF), and unbiased non-local means (UNLMF)), with 33 different settings, in T2-weighted MR images of phantoms (N = 112) and neuroblastoma patients (N = 25). Filters were discarded until the most optimal solutions were obtained according to 3 image quality metrics: peak signal-to-noise ratio (PSNR), edge-strength similarity-based image quality metric (ESSIM), and noise (standard deviation of the signal intensity of a region in the background area). The selected filters were ADFs and UNLMs. From them, 107 radiomics features preservation at 4 progressively added noise levels were studied. The ADF with a conductance of 1 and 2 iterations standardized the radiomic features, improving reproducibility and quality metrics.

Indexed as

AlgorithmsDiagnostic ImagingBiomarkersHumansReproducibility of ResultsSignal-To-Noise RatioBiomarkersDenoisingImage processingOncologic imaging biomarkersRadiomics

Identifiers

PMID34505958
PMCPMC8554919

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.