Evidence map›Paper›PMID 34505873›Full record

ArticleAmerican journal of hypertension2022

Household Air Pollution and Blood Pressure, Vascular Damage, and Subclinical Indicators of Cardiovascular Disease in Older Chinese Adults.

Thirumagal Kanagasabai, Wuxiang Xie, Li Yan, Liancheng Zhao, Ellison Carter, Dongshuang Guo, Stella S Daskalopoulou, Queenie Chan, Paul Elliott, Majid Ezzati and 5 more

Open access · hybridAbstract read
In one paragraph

Article in American journal of hypertension, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. How Do Household Energy Transitions Work?Research report (Health Effects Institute) · 2025
    Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 4 countries.

Thirumagal KanagasabaiInstitute for Health and Social Policy, and Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada.ORCID 0000-0003-2410-0105
Wuxiang XiePeking University Clinical Research Institute, Peking University Health Science Center, Beijing, China.
Li YanDepartment of Epidemiology and Biostatistics, and MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
Liancheng ZhaoFu Wai Hospital and Cardiovascular Institute, Chinese Academy of Medical Sciences, Beijing, China.
Ellison CarterDepartment of Civil and Environmental Engineering, Colorado State University, Fort Collins, Colorado, USA.
Dongshuang GuoDepartment of Cardiology,Yuxian Hospital, Yuxian, Shanxi, China.
Stella S DaskalopoulouDepartment of Medicine, Division of Internal Medicine and Division of Experimental Medicine, McGill University, Montreal, Quebec, Canada.
Queenie ChanDepartment of Epidemiology and Biostatistics, and MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.ORCID 0000-0001-9278-230X
Paul ElliottDepartment of Epidemiology and Biostatistics, and MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.ORCID 0000-0002-7511-5684
Majid EzzatiDepartment of Epidemiology and Biostatistics, and MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
Xudong YangDepartment of Building Science, Tsinghua University, Beijing, China.
Gaoqiang XiePeking University Clinical Research Institute, Peking University Health Science Center, Beijing, China.
Frank KellyEnvironmental Research Group, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
Yangfeng WuPeking University Clinical Research Institute, Peking University Health Science Center, Beijing, China.ORCID 0000-0002-4451-1932
Jill BaumgartnerInstitute for Health and Social Policy, and Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada.
Imperial College London · GBMcGill University · CAPeking University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNColorado State University · USMRC Centre for Environment and HealthTsinghua University · CNYuxian People's Hospital · CN

Funding

INTL POPULATION STUDY ON MACRONUTRIENTS AND BP INTERMAPR01HL050490 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DAVIGLUS, MARTHA L, ELLIOTT, PAUL · 1995 to 2013
$7.3M
Metabolomics-Measured Urinary Metabolites, Diet & BP, 17 Population Samples: INTER01HL084228 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DAVIGLUS, MARTHA L, ELLIOTT, PAUL · 2007 to 2014
$4.2M
Metabolic Pathways Underlying the Contrasting Sodium-BP and DASH/OmniHeart-BP RelationshipsR01HL135486 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DAVIGLUS, MARTHA L, ELLIOTT, PAUL · 2017 to 2020
$2.6M
AMINO ACIDS IN URINE, DIET &BP: INT'L POPULATION STUDYR01HL065461 · NHLBI · NORTHWESTERN UNIVERSITY · PI DAVIGLUS, MARTHA L · 2000 to 2003
$1.0M
NHLBI NIH HHS R01 HL050490NHLBI NIH HHS R01 HL065461NHLBI NIH HHS R01 HL084228NHLBI NIH HHS R01 HL135486NIH HHS R01-HL50490Wellcome TrustWellcome Trust 103906/Z/14/Z
6 · The paper itself

Abstract

backgroundLimited data suggest that household air pollution from cooking and heating with solid fuel (i.e., coal and biomass) stoves may contribute to the development of hypertension and vascular damage.

methodsUsing mixed-effects regression models, we investigated the associations of household air pollution with blood pressure (BP) and vascular function in 753 adults (ages 40-79 years) from 3 diverse provinces in China. We conducted repeated measures of participants' household fuel use, personal exposure to fine particulate air pollution (PM2.5), BP, brachial-femoral pulse wave velocity (bfPWV), and augmentation index. Ultrasound images of the carotid arteries were obtained to assess intima-media thickness (CIMT) and plaques. Covariate information on sociodemographics, health behaviors, 24-h urinary sodium, and blood lipids was also obtained.

resultsAverage estimated yearly personal exposure to PM2.5 was 97.5 µg/m3 (SD: 79.2; range: 3.5-1241), and 65% of participants cooked with solid fuel. In multivariable models, current solid fuel use was associated with higher systolic (2.4 mm Hg, 95% CI: -0.4, 4.9) and diastolic BP (1.4 mm Hg, 95% CI: -0.1, 3.0) and greater total area of plaques (1.7 mm2, 95% CI: -6.5, 9.8) compared with exclusive use of electricity or gas stoves. A 1 - ln(µg/m3) increase in PM2.5 exposure was associated with higher systolic (1.5 mm Hg, 95% CI: 0.2, 2.7) and diastolic BP (1.0 mm Hg, 95% CI: 0.4, 1.7) and with greater CIMT (0.02 mm, 95% CI: 0.00, 0.04) and total area of plaques (4.7 mm2, 95% CI: -2.0, 11.5). We did not find associations with arterial stiffness, except for a lower bfPWV (-1.5 m/s, 95% CI: -3.0, -0.0) among users of solid fuel heaters.

conclusionsThese findings add to limited evidence that household air pollution is associated with higher BP and with greater CIMT and total plaque area.

Indexed as

Air PollutantsAir PollutionCardiovascular DiseasesPlaque, AtheroscleroticAdultAgedBlood PressureCarotid Intima-Media ThicknessChinaEnvironmental ExposureHumansMiddle AgedParticulate MatterPulse Wave AnalysisAir PollutantsParticulate Matterarterial stiffnessatherosclerosisblood pressurefine particulate matterhypertensionplaquessolid fuel

Identifiers

PMID34505873
PMCPMC8807175
OpenAlexW3197886274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.