ArticleeLife2021
Coherent theta activity in the medial and orbital frontal cortices encodes reward value.
Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Sensorimotor Theta Oscillations Coordinate Speech Movements.bioRxiv : the preprint server for biology · 2025Article
- Phase synchrony between prefrontal noradrenergic and cholinergic signals indexes inhibitory control.Nature communications · 2025Article
- Interhemispheric EEG coherence as a candidate biomarker in gambling disorder: evidence of frontal hyperconnectivity and posterior disconnectivity.Frontiers in neuroscience · 2025Article
- Orbitofrontal and Prelimbic Cortices Serve Complementary Roles in Adapting Reward Seeking to Learned Anxiety.Biological psychiatry · 2024Article
- Article
- Beta and theta oscillations track effort and previous reward in the human basal ganglia and prefrontal cortex during decision making.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Beta and theta oscillations track effort and previous reward in human basal ganglia and prefrontal cortex during decision making.bioRxiv : the preprint server for biology · 2023Article
- Behavioral State-Dependent Modulation of Prefrontal Cortex Activity by Respiration.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Mechanisms of Sleep/Wake Regulation under Hypodopaminergic State: Insights from MitoPark Mouse Model of Parkinson's Disease.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Prefrontal network engagement by deep brain stimulation in limbic hubs.Frontiers in human neuroscience · 2023Article
- Theta oscillations in anterior cingulate cortex and orbitofrontal cortex differentially modulate accuracy and speed in flexible reward learning.Oxford open neuroscience · 2023Article
- The rostral medial frontal cortex is crucial for engagement in consummatory behavior.Behavioral neuroscience · 2022Article
- Medial prefrontal cortex lesions disrupt prepotent action selection signals in dorsomedial striatum.Current biology : CB · 2022Article
- Coherent theta activity in the medial and orbital frontal cortices encodes reward value.eLife · 2021Article
- Diminished Cortical Excitation and Elevated Inhibition During Perceptual Impairments in a Mouse Model of Autism.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
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Authors and funding
2 authors.
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Abstract
This study examined how the medial frontal (MFC) and orbital frontal (OFC) cortices process reward information. We simultaneously recorded local field potentials in the two areas as rats consumed liquid sucrose rewards. Both areas exhibited a 4-8 Hz 'theta' rhythm that was phase-locked to the lick cycle. The rhythm tracked shifts in sucrose concentrations and fluid volumes, demonstrating that it is sensitive to differences in reward magnitude. The coupling between the rhythm and licking was stronger in MFC than OFC and varied with response vigor and absolute reward value in the MFC. Spectral analysis revealed zero-lag coherence between the cortical areas, and found evidence for a directionality of the rhythm, with MFC leading OFC. Our findings suggest that consummatory behavior generates simultaneous theta range activity in the MFC and OFC that encodes the value of consumed fluids, with the MFC having a top-down role in the control of consumption.
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