Evidence map›Paper›PMID 34505734›Full record

ArticleJournal of veterinary internal medicine2021

Exercise-induced airflow changes in horses with asthma measured by electrical impedance tomography.

Nicolas Herteman, Martina Mosing, Andreas D Waldmann, Vinzenz Gerber, Angelika Schoster

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Nicolas HertemanClinic for Equine Internal Medicine, Equine Hospital, Vetsuisse Faculty, University of Zurich, Switzerland.ORCID https://orcid.org/0000-0001-8851-7714
Martina MosingSchool of Veterinary Medicine, College of Science, Health, Engineering and Education, Murdoch University, Perth, Australia.
Andreas D WaldmannDepartment of Anesthesiology and Intensive Care Medicine, Rostock University Medical Center, Rostock, Germany.
Vinzenz GerberEquine Clinic, Swiss Institute of Equine Medicine, University of Bern and Agroscope, Berne, Switzerland.
Angelika SchosterClinic for Equine Internal Medicine, Equine Hospital, Vetsuisse Faculty, University of Zurich, Switzerland.ORCID https://orcid.org/0000-0002-2162-6550
University of Zurich · CHMurdoch University · AUUniversity of Bern · CHUniversity of Rostock · DE

Funding

Fond Karin GroteStiftung Symphasis
6 · The paper itself

Abstract

backgroundEquine asthma (EA) causes airflow impairment, which increases in severity with exercise. Electrical impedance tomography (EIT) is an imaging technique that can detect airflow changes in standing healthy horses during a histamine provocation test.

objectivesTo explore EIT-calculated flow variables before and after exercise in healthy horses and horses with mild-to-moderate (MEA) and severe equine asthma (SEA). ANIMALS: Nine healthy horses 9 horses diagnosed with MEA and 5 with SEA were prospectively included.

methodsRecordings were performed before and after 15 minutes of lunging. Absolute values from global and regional peak inspiratory (PIF, positive value) and expiratory (PEF, negative value) flows were calculated. Data were analyzed using a mixed model analysis followed by Bonferroni's multiple comparisons test to evaluate the impact of exercise and diagnosis on flow indices.

resultsControl horses after exercise had significantly lower global PEF and PIF compared to horses with SEA (mean difference [95% confidence interval, CI]: 0.0859 arbitrary units [AU; 0.0339-0.1379], P < .001 and 0.0726 AU [0.0264-0.1188], P = .001, respectively) and horses with MEA (0.0561 AU [0.0129-0.0994], P = .007 and 0.0587 AU [0.0202-0.0973], P = .002, respectively). No other significant differences were detected. CONCLUSIONS AND CLINICAL IMPORTANCE: Electrical impedance tomography derived PIF and PEF differed significantly between healthy horses and horses with SEA or MEA after exercise, but not before exercise. Differences between MEA and SEA were not observed, but the study population was small.

Indexed as

AsthmaHorse DiseasesAnimalsElectric ImpedanceHorsesLungRespirationTomography, X-Ray Computedheavesinflammatory airway diseasepulmonary function testrecurrent airway obstruction

Identifiers

PMID34505734
PMCPMC8478024
OpenAlexW3198452565

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.