Evidence map›Paper›PMID 34505544›Full record

ArticlePharmacogenomics2021

Genetic factors in treatment-related cardiovascular complications in survivors of childhood acute lymphoblastic leukemia.

Kateryna Petrykey, Aziz M Rezgui, Mathilde Le Guern, Patrick Beaulieu, Pascal St-Onge, Simon Drouin, Laurence Bertout, Fan Wang, Jessica L Baedke, Yutaka Yasui and 6 more

Open access · greenAbstract read
In one paragraph

Article in Pharmacogenomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Review
  7. Genetic Factors and Long-term Treatment-Related Neurocognitive Deficits, Anxiety, and Depression in Childhood Leukemia Survivors: An Exome-Wide Association Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 2 countries.

Kateryna PetrykeyImmune Diseases and Cancer Research Axis, Sainte-Justine University Health Center (SJUHC), Montreal, QC H3T 1C5, Canada.ORCID 0000-0002-5865-3907
Aziz M RezguiImmune Diseases and Cancer Research Axis, Sainte-Justine University Health Center (SJUHC), Montreal, QC H3T 1C5, Canada.
Mathilde Le GuernImmune Diseases and Cancer Research Axis, Sainte-Justine University Health Center (SJUHC), Montreal, QC H3T 1C5, Canada.
Patrick BeaulieuImmune Diseases and Cancer Research Axis, Sainte-Justine University Health Center (SJUHC), Montreal, QC H3T 1C5, Canada.
Pascal St-OngeImmune Diseases and Cancer Research Axis, Sainte-Justine University Health Center (SJUHC), Montreal, QC H3T 1C5, Canada.
Simon DrouinImmune Diseases and Cancer Research Axis, Sainte-Justine University Health Center (SJUHC), Montreal, QC H3T 1C5, Canada.
Laurence BertoutImmune Diseases and Cancer Research Axis, Sainte-Justine University Health Center (SJUHC), Montreal, QC H3T 1C5, Canada.
Fan WangDepartment of Epidemiology & Cancer Control, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Jessica L BaedkeDepartment of Epidemiology & Cancer Control, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Yutaka YasuiDepartment of Epidemiology & Cancer Control, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID 0000-0002-7717-8638
Melissa M HudsonDepartment of Epidemiology & Cancer Control, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID 0000-0001-6984-2407
Marie-Josée RaboissonDepartment of Pediatrics, Université de Montréal, QC, H3T 1C5, Canada.
Caroline LaverdièreImmune Diseases and Cancer Research Axis, Sainte-Justine University Health Center (SJUHC), Montreal, QC H3T 1C5, Canada.
Daniel SinnettImmune Diseases and Cancer Research Axis, Sainte-Justine University Health Center (SJUHC), Montreal, QC H3T 1C5, Canada.ORCID 0000-0003-3625-6676
Gregor U AndelfingerDepartment of Pediatrics, Université de Montréal, QC, H3T 1C5, Canada.ORCID 0000-0002-9047-0502
Maja KrajinovicImmune Diseases and Cancer Research Axis, Sainte-Justine University Health Center (SJUHC), Montreal, QC H3T 1C5, Canada.ORCID 0000-0003-4772-7031
Centre Hospitalier Universitaire Sainte-Justine · CASt. Jude Children's Research Hospital · US

Funding

The St. Jude Lifetime CohortU01CA195547 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI HUDSON, MELISSA M, NESS, KIRSTEN KIMBERLIE · 2015 to 2024
$14.9M
CIHR 118694NCI NIH HHS U01 CA195547
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cancer SurvivorsAdolescentAdultAntineoplastic AgentsCardiovascular DiseasesChildChild, PreschoolCohort StudiesExome SequencingFemaleGenetic VariationHumansMalePrecursor Cell Lymphoblastic Leukemia-LymphomaYoung AdultAntineoplastic Agentsanthracycline-induced cardiotoxicitycancer survivorschildhood acute lymphoblastic leukemiadoxorubicingenetic association studieslate adverse effectspharmacogenomic markerswhole-exome sequencing

Identifiers

PMID34505544
PMCPMC9043873
OpenAlexW3196320824

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.