ReviewOral health & preventive dentistry2021
Oral Infections and Systemic Health - More than Just Links to Cardiovascular Diseases.
Review in Oral health & preventive dentistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Examining the link between tooth loss and multiple health outcomes: a comprehensive synthesis of evidence from meta-analyses.Frontiers in public health · 2026Pooled it
- Is There Any Association Between Periodontitis and Prostatic Alterations? A Systematic Review.The Prostate · 2025Pooled it
- An umbrella review of the evidence linking oral health and systemic noncommunicable diseases.Nature communications · 2022Pooled it
- The effect of antimicrobial photodynamic therapy on periodontal disease and glycemic control in patients with type 2 diabetes mellitus.Clinical oral investigations · 2023Trial
- An Empty Scoping Review on the Financing of Necrotizing Periodontal Disease Prevention and Control in Africa: Implications for Global Oral Health Research, Policy, and Practice.Health science reports · 2026Review
- Emerging Role of the NLRP3 Inflammasome in the Onset of Oral Diseases and Its Potential as a Therapeutic Target.International journal of molecular sciences · 2026Review
- Association of health-promoting behaviors with oral health status among Turkish dental students: a cross-sectional study.BMC medical education · 2026Article
- The Toothbrushing Boost Toolbox: competence-building behavioral strategies for oral health.Frontiers in public health · 2026Review
- Periodontitis and Systemic Inflammatory Multimorbidity: Narrative Review of Literature.Journal of pharmacy & bioallied sciences · 2025Article
- Oral health care use characteristics in a limited sample of Medicare Advantage beneficiaries, Medicare Advantage Encounter data 2021.Journal of the American Dental Association (1939) · 2025Article
- Oral frailty and its influencing factors in patients with cancer undergoing chemotherapy: a cross-sectional study.BMC oral health · 2025Article
- An Assessment of Periodontal Status and Oral Hygiene in Patients with Hypertension in the South-West Region of Romania.Biomedicines · 2025Article
- Dental fear and perceived oral health importance: A mediation analysis of courage as virtue.Bioinformation · 2025Article
- The relationship between cause of death and skeletal markers of physiological stress in the Hamann-Todd collection.American journal of biological anthropology · 2025Article
- Bridging Nutrition and Dentistry: An Interprofessional Education (IPE) Experience Model.Journal of multidisciplinary healthcare · 2025Article
- Periodontal Disease and Metabolic Syndrome in Women at Prior High Risk for Gestational Diabetes.Clinical and experimental dental research · 2024Article
- Modelling of Cetylpyridinium Chloride Availability in Complex Mixtures for the Prediction of Anti-Microbial Activity Using Diffusion Ordered Spectroscopy, Saturation Transfer Difference and 1D NMR.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Operationalisation of Successful Ageing in the Oral Health Context: A Citation Analysis.International dental journal · 2024Review
- Dentitions of Long-Term Care Residents: Tooth Types, Roles in Occlusion and Association with Dementia.Healthcare (Basel, Switzerland) · 2024Article
- Necessity and influencing factors for integrating oral health in cancer care for older people: a narrative review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeDuring the past 20 years, a plethora of research reports has been published showing a statistical association between poor oral health and cardiovascular diseases. The aim of this narrative review was to focus on associations between oral infections and non-atherosclerosis-related systemic diseases. MATERIALS AND
methodsAn open literature search and evaluation of articles were conducted on Medline and Cochrane databases with the key words 'oral infection', 'periodontitis', 'pneumonia', 'osteoarthritis', 'rheumatic diseases', 'inflammatory bowel disease', 'kidney disease', 'liver diseases', 'metabolic syndrome', 'diabetes', 'cancer', 'Alzheimer's disease'. Cardiovascular diseases were excluded from the analysis.
resultsThe scarcity of controlled studies did not allow conducting a systematic review with meta-analysis on the topics, but dental infections have been shown be associated with several general diseases also beyond the atherosclerosis paradigm. However, there is no causal evidence of the role of dental infections in this regard. Poor oral health has nevertheless often been observed to be associated with worsening of the diseases and may also affect treatments.
conclusionsMaintaining good oral health is imperative regarding many diseases, and its importance in the daily life of any patient group cannot be over emphasised.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.