Evidence map›Paper›PMID 34505397›Full record

ArticleJournal of applied clinical medical physics2021

Comparison of combinations of irradiation techniques and jaw conditions in intensity-modulated radiotherapy for lung cancer.

Qinghe Peng, Junyue Shi, Jun Zhang, Qiwen Li, Zhenghuan Li, Qingyuan Zhang, Yinglin Peng, Li Chen

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Qinghe PengDepartment of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.
Junyue ShiDepartment of Radiation Oncology, Foresea Life Insurance Guangzhou General Hospital, Guangzhou, China.
Jun ZhangDepartment of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.
Qiwen LiDepartment of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.
Zhenghuan LiDepartment of Radiation Oncology, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Qingyuan ZhangDepartment of Radiation Oncology, Guangzhou Concord Cancer Center, Guangzhou, China.
Yinglin PengDepartment of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.
Li ChenDepartment of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.ORCID https://orcid.org/0000-0002-9887-3429
Sun Yat-sen University · CNGeneral Hospital of Guangzhou Military Command · CN

Funding

Cancer Precision Radiotherapy Spark Program of China International Medical Foundation 2019-N-11-20Guangdong Esophageal Cancer Institute Science Q201907Guangdong Esophageal Cancer Institute Science Q201908National Natural Science Foundation of China 12005316National Natural Science Foundation of China 12075329
6 · The paper itself

Abstract

purposeTo assist in the selection of a suitable combination of an irradiation technique and jaw condition in intensity-modulated radiotherapy (IMRT) and volumetric-modulated arc radiotherapy (VMAT) for lung cancer treatment plans. MATERIALS AND

methodsThirty patients with lung cancer who underwent radiotherapy were enrolled retrospectively. They were categorized as having central lung cancer, peripheral lung cancer with mediastinal lymph node metastasis (peripheral E lung cancer), and peripheral lung cancer without mediastinal lymph node metastasis (peripheral N lung cancer). Four treatment plans were designed for each patient: fixed jaw and adaptive jaw IMRT technique (FJ-IMRT and JA-IMRT), and fixed jaw and jaw tracking VMAT technique (FJ-VMAT and JT-VMAT). The dose parameters of the four group plans were compared and analyzed.

resultsCompared to FJ-IMRT, JA-IMRT significantly reduced the mean dose (D

conclusionBased on the dosimetric findings and considering clinical data published on lung and heart side effects, we propose recommendations on the preferred treatment technique based on tumor location and pulmonary function. For central lung cancer with normal pulmonary function, we advise JT-VMAT techniques. Conversely, for central lung cancer with poor pulmonary function, we recommend JA-IMRT techniques. We advocate JA-IMRT for peripheral E lung cancer. For peripheral N lung cancer, JT-VMAT techniques are strongly recommended.

Indexed as

Lung NeoplasmsRadiotherapy, Intensity-ModulatedHumansOrgans at RiskRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRetrospective Studiesadaptive jawIMRTjaw trackinglung cancerVMAT

Identifiers

PMID34505397
PMCPMC8504584
OpenAlexW3198321074

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.