ArticleAnnals of neurology2021
Seizures after Ischemic Stroke: A Matched Multicenter Study.
Article in Annals of neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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Who cites it
52 citing papers in PubMed, 101 citations in OpenAlex.
- Frequency of seizures in post-cerebrovascular accident patients.Pakistan journal of medical sciences · 2026Article
- Continuous Versus Short EEG After Ischemic Stroke: What cEEG Adds for Detecting Abnormalities and Predicting Post-Stroke Epilepsy.Annals of neurology · 2026Article
- From Acute Symptomatic Seizures to Post-Stroke Epilepsy: A Narrative Review of Diagnosis and Management.Journal of clinical medicine · 2026Review
- Convulsive-Like Movements in Posterior Circulation Large Vessel Occlusion: Associations With Midbrain Injury and Poor Outcome.CNS neuroscience & therapeutics · 2026Article
- The incidence and impact of early post-stroke seizures for successful endovascular stroke treatment: an individual patient data level analysis of trials.International journal of surgery (London, England) · 2026Article
- Electroencephalography in stroke Care: From acute monitoring to Post-Stroke epilepsy.Clinical neurophysiology practice · 2026Review
- Associations of Late-Onset Epilepsy With Myocardial Infarction and Nonstroke Vascular Death.Neurology · 2025Article
- Epilepsy as a dynamic disease: Toward actionable, individualized seizure risk prediction.Epilepsia · 2025Review
- The Role of Electroencephalography in Predicting Post-Stroke Seizures and an Updated Prognostic Model (SeLECT-EEG).Annals of neurology · 2025Article
- Reperfusion Therapies and Post-Stroke Seizures: Evidence, Mechanisms and Clinical Implications-A Narrative Review.The Malaysian journal of medical sciences : MJMS · 2025Review
- Risk factors of epilepsy recurrence in patients with post-stroke epilepsy.Pakistan journal of medical sciences · 2025Article
- New advances in Traditional Chinese Medicine interventions for epilepsy: where are we and what do we know?Chinese medicine · 2025Review
- Antiseizure medications for primary and secondary seizure prevention after stroke.Frontiers in neurology · 2025Review
- Revascularization Therapies for Ischemic Stroke and Association With Risk of Epilepsy: A Danish Nationwide Register-Based Study.Journal of the American Heart Association · 2024Article
- Causal relations between ischemic stroke and epilepsy: A bidirectional Mendelian randomization study.Heliyon · 2024Article
- Pathophysiology, Diagnosis, Prognosis, and Prevention of Poststroke Epilepsy: Clinical and Research Implications.Neurology · 2024Review
- The Association of Epileptic Seizures after Acute Ischemic Stroke with Cerebral Cortical Involvement and Electroencephalographic Changes.Medicina (Kaunas, Lithuania) · 2024Article
- Cerebral small vessel disease increases risk for epilepsy: a Mendelian randomization study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Role of the glymphatic system and perivascular spaces as a potential biomarker for post-stroke epilepsy.Epilepsia open · 2024Review
- Migraine - a borderland disease to epilepsy: near it but not of it.The journal of headache and pain · 2024Review
Corrections and comments
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Authors and funding
37 authors at 11 institutions in 11 countries.
Funding
Abstract
objectiveThe purpose of this study was to identify risk factors for acute symptomatic seizures and post-stroke epilepsy after acute ischemic stroke and evaluate the effects of reperfusion treatment.
methodsWe assessed the risk factors for post-stroke seizures using logistic or Cox regression in a multicenter study, including adults from 8 European referral centers with neuroimaging-confirmed ischemic stroke. We compared the risk of post-stroke seizures between participants with or without reperfusion treatment following propensity score matching to reduce confounding due to treatment selection.
resultsIn the overall cohort of 4,229 participants (mean age 71 years, 57% men), a higher risk of acute symptomatic seizures was observed in those with more severe strokes, infarcts located in the posterior cerebral artery territory, and strokes caused by large-artery atherosclerosis. Strokes caused by small-vessel occlusion carried a small risk of acute symptomatic seizures. 6% developed post-stroke epilepsy. Risk factors for post-stroke epilepsy were acute symptomatic seizures, more severe strokes, infarcts involving the cerebral cortex, and strokes caused by large-artery atherosclerosis. Electroencephalography findings within 7 days of stroke onset were not independently associated with the risk of post-stroke epilepsy. There was no association between reperfusion treatments in general or only intravenous thrombolysis or mechanical thrombectomy with the time to post-stroke epilepsy or the risk of acute symptomatic seizures.
interpretationPost-stroke seizures are related to stroke severity, etiology, and location, whereas an early electroencephalogram was not predictive of epilepsy. We did not find an association of reperfusion treatment with risks of acute symptomatic seizures or post-stroke epilepsy. ANN NEUROL 2021;90:808-820.
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