Evidence map›Paper›PMID 34504949›Full record

ArticleChemPhotoChem2021

Photophysical Properties of Indocyanine Green in the Shortwave Infrared Region.

Emily D Cosco, Irene Lim, Ellen M Sletten

Abstract read
In one paragraph

Article in ChemPhotoChem, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
  2. Article
  3. De Novo Design of Near-Infrared Fluorescence-Activating Proteins.Journal of the American Chemical Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emily D CoscoDr. E. D. Cosco, I. Lim, Prof. E. M. Sletten Department of Chemistry and Biochemistry, California NanoSystems Institute, University of California, Los Angeles, 607 Charles E. Young Dr. East, Los Angeles, CA 90095 (USA).
Irene LimDr. E. D. Cosco, I. Lim, Prof. E. M. Sletten Department of Chemistry and Biochemistry, California NanoSystems Institute, University of California, Los Angeles, 607 Charles E. Young Dr. East, Los Angeles, CA 90095 (USA).
Ellen M SlettenDr. E. D. Cosco, I. Lim, Prof. E. M. Sletten Department of Chemistry and Biochemistry, California NanoSystems Institute, University of California, Los Angeles, 607 Charles E. Young Dr. East, Los Angeles, CA 90095 (USA).

Funding

Biocompatible fluorophores for shortwave infrared imagingR01EB027172 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Ellen May Sletten · 2019 to 2026
$2.9M
Multiphoton Microscope for Deep Tissue ImagingS10OD025017 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BENTOLILA, LAURENT A. · 2018 to 2018
$599k
Quantitative Mass Spectrometer for Targeted and Global Proteomics, MetabolomicsS10OD016387 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GRAEBER, THOMAS G · 2013 to 2013
$593k
NIBIB NIH HHS R01 EB027172NIH HHS S10 OD016387NIH HHS S10 OD025017
6 · The paper itself

Abstract

With the growing development of new contrast agents for optical imaging using near-infrared and shortwave infrared (SWIR) wavelengths, it is essential to have consistent bench-marks for emitters in these regions. Indocyanine green (ICG), a ubiquitous and FDA-approved organic dye and optical imaging agent, is commonly employed as a standard for photophysical properties and biological performance for imaging experiments at these wavelengths. Yet, its reported photophysical properties across organic and aqueous solvents vary greatly in the literature, which hinders its ability to be used as a consistent benchmark. Herein, we measure photophysical properties in organic and aqueous solvents using InGaAs detection (~950-1,700 nm), providing particular relevance for SWIR imaging.

Indexed as

chromophoresdyes/pigmentsimaging agentsnear-infraredphotophysical properties

Identifiers

PMID34504949
PMCPMC8423351

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.