Evidence map›Paper›PMID 34504868›Full record

ArticleFrontiers in molecular biosciences2021

Coarse-Grained Modeling and Molecular Dynamics Simulations of Ca

Jules Nde, Pengzhi Zhang, Jacob C Ezerski, Wei Lu, Kaitlin Knapp, Peter G Wolynes, Margaret S Cheung

Abstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. CaProtein science : a publication of the Protein Society · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jules NdeDepartment of Physics, University of Houston, Houston, TX, United States.
Pengzhi ZhangDepartment of Physics, University of Houston, Houston, TX, United States.
Jacob C EzerskiDepartment of Physics, University of Houston, Houston, TX, United States.
Wei LuCenter for Theoretical Biological Physics, Rice University, Houston, TX, United States.
Kaitlin KnappCenter for Theoretical Biological Physics, Rice University, Houston, TX, United States.
Peter G WolynesCenter for Theoretical Biological Physics, Rice University, Houston, TX, United States.
Margaret S CheungDepartment of Physics, University of Houston, Houston, TX, United States.

Funding

Principles for Tuning Target Selectivity in Signaling ProteinsR01GM097553 · NIGMS · UNIVERSITY OF WASHINGTON · PI CHEUNG, MARGARET SHUN · 2011 to 2022
$2.7M
NIGMS NIH HHS R01 GM097553
6 · The paper itself

Abstract

Calmodulin (CaM) is a calcium-binding protein that transduces signals to downstream proteins through target binding upon calcium binding in a time-dependent manner. Understanding the target binding process that tunes CaM's affinity for the calcium ions (Ca

Indexed as

AWSEMcalcium-binding proteincalmodulin dynamicscommunity modelconformational changesintrinsic disorder

Identifiers

PMID34504868
PMCPMC8421859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.