Evidence map›Paper›PMID 34504861›Full record

ReviewFrontiers in nutrition2021

Marine-Derived Collagen as Biomaterials for Human Health.

Ning Xu, Xue-Liang Peng, Hao-Ru Li, Jia-Xuan Liu, Ji-Si-Yu Cheng, Xin-Ya Qi, Shao-Jie Ye, Hai-Lun Gong, Xiao-Hong Zhao, Jiangming Yu and 2 more

Abstract readReview
In one paragraph

Review in Frontiers in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Review
  3. Assessment of Bovine Collagen Manufactured via Cellular Agriculture.ACS biomaterials science & engineering · 2026
    Article
  4. Article
  5. International journal of molecular sciences · 2025
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Identification and Antimicrobial Potential of Marine Sponges (International journal of microbiology · 2025
    Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ning XuDepartment of Orthopedics, Second Affiliated Hospital, Naval Medical University, Shanghai, China.
Xue-Liang PengKey Laboratory of Resource Biology and Biotechnology in Western China, Department of Life Sciences and Medicine, Ministry of Education, School of Medicine, Northwest University, Xi'an, China.
Hao-Ru LiKey Laboratory of Resource Biology and Biotechnology in Western China, Department of Life Sciences and Medicine, Ministry of Education, School of Medicine, Northwest University, Xi'an, China.
Jia-Xuan LiuKey Laboratory of Resource Biology and Biotechnology in Western China, Department of Life Sciences and Medicine, Ministry of Education, School of Medicine, Northwest University, Xi'an, China.
Ji-Si-Yu ChengKey Laboratory of Resource Biology and Biotechnology in Western China, Department of Life Sciences and Medicine, Ministry of Education, School of Medicine, Northwest University, Xi'an, China.
Xin-Ya QiKey Laboratory of Resource Biology and Biotechnology in Western China, Department of Life Sciences and Medicine, Ministry of Education, School of Medicine, Northwest University, Xi'an, China.
Shao-Jie YeKey Laboratory of Resource Biology and Biotechnology in Western China, Department of Life Sciences and Medicine, Ministry of Education, School of Medicine, Northwest University, Xi'an, China.
Hai-Lun GongKey Laboratory of Resource Biology and Biotechnology in Western China, Department of Life Sciences and Medicine, Ministry of Education, School of Medicine, Northwest University, Xi'an, China.
Xiao-Hong ZhaoKey Laboratory of Resource Biology and Biotechnology in Western China, Department of Life Sciences and Medicine, Ministry of Education, School of Medicine, Northwest University, Xi'an, China.
Jiangming YuDepartment of Orthopedics, Tongren Hospital, Shanghai Jiaotong University, Shanghai, China.
Guohua XuDepartment of Orthopedics, Second Affiliated Hospital, Naval Medical University, Shanghai, China.
Dai-Xu WeiKey Laboratory of Resource Biology and Biotechnology in Western China, Department of Life Sciences and Medicine, Ministry of Education, School of Medicine, Northwest University, Xi'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Collagen is a kind of biocompatible protein material, which is widely used in medical tissue engineering, drug delivery, cosmetics, food and other fields. Because of its wide source, low extraction cost and good physical and chemical properties, it has attracted the attention of many researchers in recent years. However, the application of collagen derived from terrestrial organisms is limited due to the existence of diseases, religious beliefs and other problems. Therefore, exploring a wider range of sources of collagen has become one of the main topics for researchers. Marine-derived collagen (MDC) stands out because it comes from a variety of sources and avoids issues such as religion. On the one hand, this paper summarized the sources, extraction methods and characteristics of MDC, and on the other hand, it summarized the application of MDC in the above fields. And on the basis of the review, we found that MDC can not only be extracted from marine organisms, but also from the wastes of some marine organisms, such as fish scales. This makes further use of seafood resources and increases the application prospect of MDC.

Indexed as

cosmeticsdrug delivery systemfoodhealth care productmarine-derived collagentissue engineering

Identifiers

PMID34504861
PMCPMC8421607

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.