Evidence map›Paper›PMID 34504838›Full record

ArticleFrontiers in cell and developmental biology2021

Two Novel Pathogenic Variants of

Jia Tang, Meihua Tan, Yihui Deng, Hui Tang, Haihong Shi, Mingzhen Li, Wei Ma, Jia Li, Hongzheng Dai, Jianli Li and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 2 countries.

Jia TangNHC Key Laboratory of Male Reproduction and Genetics, Guangdong Provincial Reproductive Science Institute (Guangdong Provincial Fertility Hospital), Guangzhou, China.
Meihua TanCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Yihui DengDepartment of Medical Imaging Center, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, China.
Hui TangDepartment of Medical Imaging Center, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, China.
Haihong ShiMedical Genetics Center, Jiangmen Maternity and Child Health Care Hospital, Jiangmen, China.
Mingzhen LiNHC Key Laboratory of Male Reproduction and Genetics, Guangdong Provincial Reproductive Science Institute (Guangdong Provincial Fertility Hospital), Guangzhou, China.
Wei MaDepartment of Biology, School of Basic Medicine, Jiamusi University, Jiamusi, China.
Jia LiBGI Genomics Co., Ltd., Shenzhen, China.
Hongzheng DaiDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, United States.
Jianli LiDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, United States.
Shengmei ZhouDepartment of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Xu LiKey Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China.
Fengxiang WeiLonggang District Maternity & Child Healthcare Hospital of Shenzhen City, Shenzhen, China.
Xiaofen MaDepartment of Medical Imaging of Guangdong Second Provincial General Hospital, Guangzhou, China.
Liangping LuoDepartment of Medical Imaging Center, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, China.
Baylor College of Medicine · USFirst Affiliated Hospital of Jinan University · CNBGI Group (China) · CNChildren's Hospital of Los Angeles · USGuangdong Provincial People's Hospital · CNJiamusi University · CNShenzhen Maternity and Child Healthcare Hospital · CNWestlake University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progressive familial intrahepatic cholestasis (PFIC) is an autosomal recessive inherited disease that accounts for 10%-15% childhood cholestasis and could lead to infant disability or death. There are three well-established types of PFIC (1-3), caused by mutations in the

Indexed as

cytoskeletonmolecular mechanismnovel pathogenic variantPFICTJP2

Identifiers

PMID34504838
PMCPMC8421653
OpenAlexW3195541974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.