Evidence map›Paper›PMID 34504785›Full record

ArticleFrontiers in oncology2021

A Retrospective Observation of Treatment Outcomes Using Decitabine-Combined Standard Conditioning Regimens Before Transplantation in Patients With Relapsed or Refractory Acute Myeloid Leukemia.

Yuhang Li, Longcan Cheng, Chen Xu, Jianlin Chen, Jiangwei Hu, Na Liu, Sanchun Lan, Jing Xie, Ting Sun, Lei Wang and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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  4. Review
  5. Article
  6. Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Yuhang LiDepartment of Hematology, 5th Medical Center of Chinese PLA General Hospital, Beijing, China.
Longcan ChengDepartment of Hematology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.
Chen XuDepartment of Hematology, 5th Medical Center of Chinese PLA General Hospital, Beijing, China.
Jianlin ChenDepartment of Hematology, 5th Medical Center of Chinese PLA General Hospital, Beijing, China.
Jiangwei HuDepartment of Hematology, 5th Medical Center of Chinese PLA General Hospital, Beijing, China.
Na LiuDepartment of Hematology, 5th Medical Center of Chinese PLA General Hospital, Beijing, China.
Sanchun LanDepartment of Hematology, 5th Medical Center of Chinese PLA General Hospital, Beijing, China.
Jing XieDepartment of Hematology, 5th Medical Center of Chinese PLA General Hospital, Beijing, China.
Ting SunDepartment of Hematology, 5th Medical Center of Chinese PLA General Hospital, Beijing, China.
Lei WangDepartment of Hematology, 5th Medical Center of Chinese PLA General Hospital, Beijing, China.
Yu ZhangDepartment of Hematology, 5th Medical Center of Chinese PLA General Hospital, Beijing, China.
Yao SunDepartment of Hematology, 5th Medical Center of Chinese PLA General Hospital, Beijing, China.
Shuiping ChenDepartment of Laboratory Medicine, 5th Medical Center of Chinese PLA General Hospital, Beijing, China.
Liangding HuDepartment of Hematology, 5th Medical Center of Chinese PLA General Hospital, Beijing, China.
Chinese PLA General Hospital · CNHainan General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypomethylating agents, decitabine (DAC) and azacitidine, can act as prophylactic and pre-emptive approaches after allogeneic hematopoietic stem cell transplantation (allo-HSCT) and a non-intensive bridging approach before allo-HSCT. However, they are rarely used as a part of conditioning regimens in patients with relapsed or refractory acute myeloid leukemia (AML). This retrospectively study included a total of 65 patients (median, 37; range, 13-63) with relapsed or refractory AML who were treated by allo-HSCT after myeloablative conditioning regimens without or with DAC (high-dose DAC schedule, 75 mg/m

Indexed as

allogeneic hematopoietic stem cell transplantationconditioning regimendecitabinehypomethylating agentsrelapsed/refractory acute myeloid leukemia

Identifiers

PMID34504785
PMCPMC8421765
OpenAlexW3194812359

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.