Evidence map›Paper›PMID 34504707›Full record

ArticleSAGE open medicine2021

Antibiotic utilization, sensitivity, and cost in the medical intensive care unit of a tertiary care teaching hospital in Nepal.

Nirmal Raj Marasine, Shakti Shrestha, Sabina Sankhi, Nabina Paudel, Ashish Gautam, Arjun Poudel

Open access · goldAbstract read
In one paragraph

Article in SAGE open medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Nirmal Raj MarasineDepartment of Pharmacy, Karnali College of Health Science, Kathmandu, Nepal.ORCID https://orcid.org/0000-0003-4353-382X
Shakti ShresthaSchool of Pharmacy, University of Queensland, Brisbane, QLD, Australia.
Sabina SankhiDepartment of Pharmacy, Modern Technical College, Lalitpur, Nepal.
Nabina PaudelSchool of Pharmacy, Kathmandu University, Dhulikhel, Nepal.
Ashish GautamSchool of Pharmacy, Chitwan Medical College, Bharatpur, Nepal.
Arjun PoudelSchool of Clinical Sciences, Queensland University of Technology, Brisbane, QLD, Australia.
Chitwan Medical College · NPKathmandu University · NPQueensland University of Technology · AUThe University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh utilization and irrational use of antibiotics in an intensive care unit increases microbial resistance, morbidity, mortality, and costs.

objectiveThis study aimed to evaluate the utilization, sensitivity and cost analysis of antibiotics used in the medical intensive care unit of a tertiary care teaching hospital of Nepal.

methodsA prospective cohort study was conducted on patients admitted to the medical intensive care unit at a tertiary care teaching hospital in central Nepal from July to September 2016. Antibiotic utilization, defined daily dose per 100 bed-days and the cost of antibiotics per patient were calculated. Descriptive statistics were performed using IBM-SPSS 20.0.

resultsA total of 365 antibiotics were prescribed in 157 patients during the study period, with an average of 2.34 prescriptions per patient. Total antibiotic utilization in terms of defined daily dose per 100 bed-days was 49.5. Piperacillin/tazobactam (45.2%) was the most commonly prescribed antibiotic, and meropenem was the most expensive antibiotics (US$4440.70). The median (interquartile range) cost of antibiotics used per patient was US$47.67 (US$63.73).

conclusionThis study suggests that the utilization and cost of antibiotics are high in medical intensive care unit of the hospital and

Indexed as

Antibioticscost analysisdefined daily dosedrug utilization studymedical intensive care unit

Identifiers

PMID34504707
PMCPMC8422810
OpenAlexW3198553432

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.