Evidence map›Paper›PMID 34504690›Full record

ArticleF1000Research2020

Augmented ustekinumab dosing is needed to achieve clinical response in patients with anti-TNF refractory pediatric Crohn's disease: a retrospective chart review.

Phinga Do, John Andersen, Ashish Patel, Gaith Semrin, Luis Sifuentes-Dominguez, Phuong Luu, Bhaskar Gurram

Open access · goldAbstract read
In one paragraph

Article in F1000Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Saudi consensus guidance for the diagnosis and management of inflammatory bowel disease in children and adolescents.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025
    Guideline
  3. Pooled it
  4. Observational
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Phinga DoDepartment of Pediatrics, Children's Health Medical Center Dallas, Dallas, TX, 75235, USA.ORCID 0000-0003-2255-9991
John AndersenDepartment of Pediatrics, Children's Health Medical Center Dallas, Dallas, TX, 75235, USA.
Ashish PatelDepartment of Pediatrics, Children's Health Medical Center Dallas, Dallas, TX, 75235, USA.
Gaith SemrinDepartment of Pediatrics, Children's Health Medical Center Dallas, Dallas, TX, 75235, USA.
Luis Sifuentes-DominguezDepartment of Pediatrics, Children's Health Medical Center Dallas, Dallas, TX, 75235, USA.
Phuong LuuDepartment of Pediatrics, Children's Health Medical Center Dallas, Dallas, TX, 75235, USA.
Bhaskar GurramDepartment of Pediatrics, Children's Health Medical Center Dallas, Dallas, TX, 75235, USA.ORCID 0000-0003-3169-2225
Southwestern Medical Center · USMedical City Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Crohn DiseaseAdultChildHumansRetrospective StudiesTumor Necrosis Factor InhibitorsUstekinumabTumor Necrosis Factor InhibitorsUstekinumabanti-TNF-refractory Crohn's diseaseClinical responseInflammatory bowel diseasePediatric Crohn's diseaseTherapeutic drug monitoringUstekinumab

Identifiers

PMID34504690
PMCPMC8408544.2
OpenAlexW3021607135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.