Evidence map›Paper›PMID 34504685›Full record

SynthesisF1000Research2021

The role of single nucleotide polymorphisms of

Azharuddin Azharuddin, Muhammad Ilmawan, Jonny Karunia Fajar, Marhami Fahriani, Sukamto S Mamada, Helnida Anggun Maliga, Firzan Nainu, Kuldeep Dhama, Harapan Harapan, Rahadyan Magetsari

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in F1000Research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 2 citations in OpenAlex.

  1. Association ofMedicina (Kaunas, Lithuania) · 2025
    Pooled it
  2. Pooled it
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Azharuddin AzharuddinDepartment of Orthopedic and Traumatology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia.ORCID 0000-0002-2497-1640
Muhammad IlmawanFaculty of Medicine, Universitas Brawijaya, Malang, East Java, 65117, Indonesia.ORCID 0000-0002-9459-609X
Jonny Karunia FajarMedical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia.ORCID 0000-0002-0309-5813
Marhami FahrianiMedical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia.ORCID 0000-0003-0452-3485
Sukamto S MamadaFaculty of Pharmacy, Hasanuddin University, Tamalanrea, Makassar, South Sulawesi, 90245, Indonesia.ORCID 0000-0002-7813-2164
Helnida Anggun MaligaFaculty of Medicine, Universitas Brawijaya, Malang, East Java, 65117, Indonesia.
Firzan NainuFaculty of Pharmacy, Hasanuddin University, Tamalanrea, Makassar, South Sulawesi, 90245, Indonesia.ORCID 0000-0003-0989-4023
Kuldeep DhamaDivision of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, 243122, India.ORCID 0000-0001-7469-4752
Harapan HarapanMedical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia.ORCID 0000-0001-7630-8413
Rahadyan MagetsariOrthopaedic and Traumatology Division, Department of Surgery, Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, DKI Yogyakarta, 55281, Indonesia.
Universitas Syiah Kuala · IDUniversity of Brawijaya · IDHasanuddin University · IDIndian Veterinary Research Institute · INUniversitas Gadjah Mada · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Nucleus PulposusPolymorphism, Single NucleotideGenetic Predisposition to DiseaseHumansInterleukin-1alphaReceptors, CalcitriolTumor Necrosis Factor-alphaInterleukin-1alphaReceptors, CalcitriolTumor Necrosis Factor-alphaVDR protein, humanIL-1ASNPSpinal disc herniationTNF-AVDR

Identifiers

PMID34504685
PMCPMC8406444.3
OpenAlexW3164709257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.