Direct-Contact Low-Frequency Ultrasound and Pulse Lavage Eradicates Biofilms on Implant Materials In Vitro.

Xiaoqing Wu, Xuanren Shi, Mingcong Chen, Xiaoyong Chen, Chi Zhang, Xiaonan Zhang, Jinyu Zhu

Open access · hybridAbstract read

In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

1.5field-weighted citation impact, top 18% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

Biofilm Removal and Bacterial Reduction Using a Low-Cost Ultrasonic Bath Sonicator with Povidone-Iodine on Polyethylene: An In Vitro Periprosthetic Joint Infection Model.Antibiotics (Basel, Switzerland) · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiaoqing WuDepartment of Orthopaedics and Traumatology, Shenzhen University General Hospital, Shenzhen 518055, China.

Xuanren ShiDepartment of Hematology and Oncology, Shenzhen University General Hospital, Shenzhen 518055, China.

Mingcong ChenDepartment of Orthopaedics and Traumatology, Shenzhen University General Hospital, Shenzhen 518055, China.

Xiaoyong ChenDepartment of Orthopaedics and Traumatology, Shenzhen University General Hospital, Shenzhen 518055, China.

Chi ZhangDepartment of Laboratory Medicine, Shenzhen University General Hospital, Shenzhen 518055, China.

Xiaonan ZhangGuangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen 518060, China.

Jinyu ZhuDepartment of Orthopaedics and Traumatology, Shenzhen University General Hospital, Shenzhen 518055, China.ORCID https://orcid.org/0000-0002-7811-752X

Shenzhen University · CNShenzhen University Health Science Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulse lavage (PL) debridement and ultrasound are both known to be the treatment of biofilm-related periprosthetic joint infection (PJI). However, the efficacy of these in combination is unknown in eradicating biofilm from the orthopaedic metal implant surface. This study was conducted to understand the efficacy of PL and ultrasound in combination in eradicating bacterial biofilms on titanium alloy in vitro. Biofilms of

Identifiers

PMID34504531

DOI10.1155/2021/1562605

PMCPMC8423559

OpenAlexW3196971182

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.