Evidence map›Paper›PMID 34504473›Full record

ReviewFrontiers in endocrinology2021

Thyroid Dysfunction and Sleep Disorders.

Max E Green, Victor Bernet, Joseph Cheung

Registry-linked trialAbstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06331819 (Clinical Association Between Obstructive Sleep Apnea), which is not on this map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06331819 recruitingnot on this mapstarted 2024, after this paper: background citation

Clinical Association Between Obstructive Sleep Apnea (OSA) and Facial Pigmentation, and the Relation Between OSA and Vasovagal Symptoms With Resulting Smoking Tendency and the Effect of Treatment in Patients Referred for Sleep Study.

TypeobservationalSponsorJordan Collaborating Cardiology GroupRan2024 to 2026Enrolled200ConditionsObstructive Sleep Apnea, Vasovagal Syncope, Smoking, Acanthosis NigricansArmsIn-lab polysomnography, Continuous positive airway pressure, Home sleep study device
3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Max E GreenMayo Clinic School of Graduate Medical Education, Mayo Clinic College of Medicine and Science, Jacksonville, FL, United States.
Victor BernetDivision of Endocrinology, Mayo Clinic, Jacksonville, FL, United States.
Joseph CheungDivision of Pulmonary, Allergy and Sleep Medicine, Mayo Clinic, Jacksonville, FL, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid disorders and sleep disorders are common problems in the general population that can affect people of all ages, backgrounds, and sexes, but little is known about their clinical associations. We reviewed the literature assessing the associations between thyroid disease and sleep disorders and noted that hyperthyroidism and hypothyroidism have clinical overlap with sleep conditions such as insomnia, restless legs syndrome, and obstructive sleep apnea. These findings highlight the importance of identifying and managing thyroid dysfunction for patients with these common sleep disorders. Additional research is needed to further understand how thyroid dysfunction affects sleep physiology.

Indexed as

AnimalsHumansSleep Wake DisordersThyroid DiseasesThyroid Glandhyperthyroidismhypothyroidisminsomniaobstructiverestless legs syndromesleepsleep apneasleep initiation and maintenance disorders

Identifiers

PMID34504473
PMCPMC8423342

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.