Evidence map›Paper›PMID 34504449›Full record

ArticleFrontiers in psychiatry2021

Is the Combination of ADOS and ADI-R Necessary to Classify ASD? Rethinking the "Gold Standard" in Diagnosing ASD.

Inge Kamp-Becker, Johannes Tauscher, Nicole Wolff, Charlotte Küpper, Luise Poustka, Stefan Roepke, Veit Roessner, Dominik Heider, Sanna Stroth

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
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  6. Autistic Adults Anticipate Simple and Complex Narrative Events.Journal of autism and developmental disorders · 2025
    Article
  7. Pathways to autism diagnosis in adulthood.Journal of neurodevelopmental disorders · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Inge Kamp-BeckerDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Philipps University, Marburg, Germany.
Johannes TauscherDepartment of Mathematics and Computer Science, Philipps University Marburg, Marburg, Germany.
Nicole WolffDepartment of Child and Adolescent Psychiatry and Psychotherapy, Faculty of Medicine of the Technische Universität Dresden, Dresden, Germany.
Charlotte KüpperDepartment of Psychiatry, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Luise PoustkaDepartment of Child and Adolescent Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany.
Stefan RoepkeDepartment of Psychiatry, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Veit RoessnerDepartment of Child and Adolescent Psychiatry and Psychotherapy, Faculty of Medicine of the Technische Universität Dresden, Dresden, Germany.
Dominik HeiderDepartment of Mathematics and Computer Science, Philipps University Marburg, Marburg, Germany.
Sanna StrothDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Philipps University, Marburg, Germany.
Philipps University of Marburg · DECharité - Universitätsmedizin Berlin · DETU Dresden · DEUniversitätsmedizin Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnosing autism spectrum disorder (ASD) requires extensive clinical expertise and training as well as a focus on differential diagnoses. The diagnostic process is particularly complex given symptom overlap with other mental disorders and high rates of co-occurring physical and mental health concerns. The aim of this study was to conduct a data-driven selection of the most relevant diagnostic information collected from a behavior observation and an anamnestic interview in two clinical samples of children/younger adolescents and adolescents/adults with suspected ASD.

Indexed as

ADI-RADOSautism spectrum disorderclinical characteristicsdifferential diagnosis behavioral aspectsGoldstandardmachine learningrandom forest

Identifiers

PMID34504449
PMCPMC8421762
OpenAlexW3194847213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.