Evidence map›Paper›PMID 34504277›Full record

ArticleScientific reports2021

The effect of population size for pathogen transmission on prediction of COVID-19 spread.

Xuqi Zhang, Haiqi Liu, Hanning Tang, Mei Zhang, Xuedong Yuan, Xiaojing Shen

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xuqi ZhangSchool of Mathematics, Sichuan University, Chengdu, 610064, Sichuan, China.
Haiqi LiuSchool of Mathematics, Sichuan University, Chengdu, 610064, Sichuan, China. 411566818@qq.com.ORCID 0000-0003-2203-137X
Hanning TangSchool of Mathematics, Sichuan University, Chengdu, 610064, Sichuan, China.
Mei ZhangSchool of Mathematics, Sichuan University, Chengdu, 610064, Sichuan, China.
Xuedong YuanSchool of Computer Science, Sichuan University, Chengdu, 610064, Sichuan, China.
Xiaojing ShenSchool of Mathematics, Sichuan University, Chengdu, 610064, Sichuan, China.
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extreme public health interventions play a critical role in mitigating the local and global prevalence and pandemic potential. Here, we use population size for pathogen transmission to measure the intensity of public health interventions, which is a key characteristic variable for nowcasting and forecasting of COVID-19. By formulating a hidden Markov dynamic system and using nonlinear filtering theory, we have developed a stochastic epidemic dynamic model under public health interventions. The model parameters and states are estimated in time from internationally available public data by combining an unscented filter and an interacting multiple model filter. Moreover, we consider the computability of the population size and provide its selection criterion. With applications to COVID-19, we estimate the mean of the effective reproductive number of China and the rest of the globe except China (GEC) to be 2.4626 (95% CI: 2.4142-2.5111) and 3.0979 (95% CI: 3.0968-3.0990), respectively. The prediction results show the effectiveness of the stochastic epidemic dynamic model with nonlinear filtering. The hidden Markov dynamic system with nonlinear filtering can be used to make analysis, nowcasting and forecasting for other contagious diseases in the future since it helps to understand the mechanism of disease transmission and to estimate the population size for pathogen transmission and the number of hidden infections, which is a valid tool for decision-making by policy makers for epidemic control.

Indexed as

Basic Reproduction NumberCOVID-19Population DensityChinaCommunicable Disease ControlForecastingHumansModels, StatisticalPrevalencePublic HealthSARS-CoV-2

Identifiers

PMID34504277
PMCPMC8429718
OpenAlexW3197860609

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.