Evidence map›Paper›PMID 34504231›Full record

ArticleScientific reports2021

Right ventricular myocardial oxygen tension is reduced in monocrotaline-induced pulmonary hypertension in the rat and restored by myo-inositol trispyrophosphate.

Marta Oknińska, Zuzanna Zambrowska, Karolina Zajda, Aleksandra Paterek, Klaudia Brodaczewska, Urszula Mackiewicz, Cezary Szczylik, Adam Torbicki, Claudine Kieda, Michał Mączewski

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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  9. Effects of the peripheral CBFrontiers in pharmacology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Marta OknińskaDepartment of Clinical Physiology, Centre of Postgraduate Medical Education, Warsaw, Poland.
Zuzanna ZambrowskaDepartment of Clinical Physiology, Centre of Postgraduate Medical Education, Warsaw, Poland.
Karolina ZajdaLaboratory of Molecular Oncology and Innovative Therapies, Military Institute of Medicine, Warsaw, Poland.
Aleksandra PaterekDepartment of Clinical Physiology, Centre of Postgraduate Medical Education, Warsaw, Poland.
Klaudia BrodaczewskaLaboratory of Molecular Oncology and Innovative Therapies, Military Institute of Medicine, Warsaw, Poland.
Urszula MackiewiczDepartment of Clinical Physiology, Centre of Postgraduate Medical Education, Warsaw, Poland.
Cezary SzczylikDepartment of Oncology, Centre of Postgraduate Medical Education, Warsaw, Poland.
Adam TorbickiDepartment of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, Centre of Postgraduate Medical Education, Warsaw, Poland.
Claudine Kieda *Laboratory of Molecular Oncology and Innovative Therapies, Military Institute of Medicine, Warsaw, Poland.
Michał Mączewski *Department of Clinical Physiology, Centre of Postgraduate Medical Education, Warsaw, Poland. michal.maczewski@cmkp.edu.pl.ORCID 0000-0002-3157-4141
Postgraduate School of Molecular Medicine · PLWojskowy Instytut Medycyny Lotniczej · PLCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary hypertension (PH) initially results in compensatory right ventricular (RV) hypertrophy, but eventually in RV failure. This transition is poorly understood, but may be triggered by hypoxia. Measurements of RV oxygen tension (pO

Indexed as

AnimalsCardiotonic AgentsDisease Models, AnimalHemoglobinsHypertension, PulmonaryHypertrophy, Right VentricularHypoxiaInositol PhosphatesMaleMonocrotalineMyocardial ContractionRatsRats, WistarTreatment OutcomeVentricular Dysfunction, RightVentricular Function, RightCardiotonic AgentsHemoglobinsInositol Phosphatesinositol trispyrophosphateMonocrotaline

Identifiers

PMID34504231
PMCPMC8429755
OpenAlexW3168381807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.