Evidence map›Paper›PMID 34504100›Full record

ReviewNPJ biofilms and microbiomes2021

Burns and biofilms: priority pathogens and in vivo models.

Evgenia Maslova, Lara Eisaiankhongi, Folke Sjöberg, Ronan R McCarthy

Open access · goldAbstract readReview
In one paragraph

Review in NPJ biofilms and microbiomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 112 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Real-Time Detection of Burn Wound Infection via a Turn-On NIR-II Fluorescent Probe.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Cathelicidin-like Peptide for ResistantAntibiotics (Basel, Switzerland) · 2026
    Article
  14. Antibiotics (Basel, Switzerland) · 2026
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Second-generation lysocins as therapeutics for treatingAntimicrobial agents and chemotherapy · 2025
    Article
  20. Review

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Evgenia MaslovaDivision of Biosciences, Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Uxbridge, UK.
Lara EisaiankhongiDivision of Biosciences, Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Uxbridge, UK.
Folke SjöbergDepartment of Hand and Plastic Surgery, The Burn Centre, Linköping University, Linköping, Sweden.
Ronan R McCarthyDivision of Biosciences, Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Uxbridge, UK. ronan.mccarthy@brunel.ac.uk.ORCID http://orcid.org/0000-0002-7480-6352
Brunel University of London · GBLinköping University · SE

Funding

Biotechnology and Biological Sciences Research Council BB/V007823/1British Heart FoundationWellcome Trust
6 · The paper itself

Abstract

Burn wounds can create significant damage to human skin, compromising one of the key barriers to infection. The leading cause of death among burn wound patients is infection. Even in the patients that survive, infections can be notoriously difficult to treat and can cause lasting damage, with delayed healing and prolonged hospital stays. Biofilm formation in the burn wound site is a major contributing factor to the failure of burn treatment regimens and mortality as a result of burn wound infection. Bacteria forming a biofilm or a bacterial community encased in a polysaccharide matrix are more resistant to disinfection, the rigors of the host immune system, and critically, more tolerant to antibiotics. Burn wound-associated biofilms are also thought to act as a launchpad for bacteria to establish deeper, systemic infection and ultimately bacteremia and sepsis. In this review, we discuss some of the leading burn wound pathogens and outline how they regulate biofilm formation in the burn wound microenvironment. We also discuss the new and emerging models that are available to study burn wound biofilm formation in vivo.

Indexed as

BiofilmsAnimalsAnti-Bacterial AgentsBacteriaBurnsCoinfectionDisease Models, AnimalHumansMiceMothsSkinSwineWound HealingWound InfectionAnti-Bacterial Agents

Identifiers

PMID34504100
PMCPMC8429633
OpenAlexW3196038562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.