Evidence map›Paper›PMID 34504033›Full record

ArticleNeurology2021

Applying Propensity Score Methods in Clinical Research in Neurology.

Peter C Austin, Amy Ying Xin Yu, Manav V Vyas, Moira K Kapral

Abstract read
In one paragraph

Article in Neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed.

  1. Trial
  2. Article
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  5. Article
  6. Article
  7. Preserflo microshunt outcomes in pigmentary glaucoma: a propensity score-matched comparison with primary open-angle glaucoma.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  8. Article
  9. Article
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  11. Article
  12. Article
  13. Article
  14. Observational
  15. Article
  16. Article
  17. Article
  18. Article
  19. Observational
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Peter C AustinFrom ICES (P.C.A., A.Y.X.Y., M.V.V., M.K.K.), Toronto; Institute of Health Management, Policy and Evaluation (P.C.A., M.K.K.) and Divisions of Neurology (A.Y.X.Y., M.V.V.) and General Internal Medicine (M.K.K.), Department of Medicine, University of Toronto; and Sunnybrook Research Institute (P.C.A.), Toronto, Canada. peter.austin@ices.on.ca.
Amy Ying Xin YuFrom ICES (P.C.A., A.Y.X.Y., M.V.V., M.K.K.), Toronto; Institute of Health Management, Policy and Evaluation (P.C.A., M.K.K.) and Divisions of Neurology (A.Y.X.Y., M.V.V.) and General Internal Medicine (M.K.K.), Department of Medicine, University of Toronto; and Sunnybrook Research Institute (P.C.A.), Toronto, Canada.ORCID 0000-0002-7276-9551
Manav V VyasFrom ICES (P.C.A., A.Y.X.Y., M.V.V., M.K.K.), Toronto; Institute of Health Management, Policy and Evaluation (P.C.A., M.K.K.) and Divisions of Neurology (A.Y.X.Y., M.V.V.) and General Internal Medicine (M.K.K.), Department of Medicine, University of Toronto; and Sunnybrook Research Institute (P.C.A.), Toronto, Canada.ORCID 0000-0002-2953-2540
Moira K KapralFrom ICES (P.C.A., A.Y.X.Y., M.V.V., M.K.K.), Toronto; Institute of Health Management, Policy and Evaluation (P.C.A., M.K.K.) and Divisions of Neurology (A.Y.X.Y., M.V.V.) and General Internal Medicine (M.K.K.), Department of Medicine, University of Toronto; and Sunnybrook Research Institute (P.C.A.), Toronto, Canada.ORCID 0000-0002-3444-9928

Funding

CIHR PJT 166161
6 · The paper itself

Abstract

Propensity score-based analysis is increasingly being used in observational studies to estimate the effects of treatments, interventions, and exposures. We introduce the concept of the propensity score and how it can be used in observational research. We describe 4 different ways of using the propensity score: matching on the propensity score, inverse probability of treatment weighting using the propensity score, stratification on the propensity score, and covariate adjustment on the propensity score (with a focus on the first 2). We provide recommendations for the use and reporting of propensity score methods for the conduct of observational studies in neurologic research.

Indexed as

NeurologyHumansMonte Carlo MethodPropensity Score

Identifiers

PMID34504033
PMCPMC8610625

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.