Evidence map›Paper›PMID 34503541›Full record

Trial reportJournal of the International Society of Sports Nutrition2021

The effects of phosphocreatine disodium salts plus blueberry extract supplementation on muscular strength, power, and endurance.

John Paul V Anders, Tyler J Neltner, Robert W Smith, Joshua L Keller, Terry J Housh, F Joseph Daugherty, Michael S Tempesta, Alekha K Dash, Daniel J Munt, Richard J Schmidt and 1 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

John Paul V AndersDepartment of Nutrition and Human Sciences, University of Nebraska-Lincoln, Lincoln, NE, 68510, USA. janders@huskers.unl.edu.ORCID http://orcid.org/0000-0002-6416-3613
Tyler J NeltnerDepartment of Nutrition and Human Sciences, University of Nebraska-Lincoln, Lincoln, NE, 68510, USA.
Robert W SmithDepartment of Nutrition and Human Sciences, University of Nebraska-Lincoln, Lincoln, NE, 68510, USA.
Joshua L KellerDepartment of Health, Kinesiology and Sport, University of South Alabama, Mobile, AL, 36688, USA.
Terry J HoushDepartment of Nutrition and Human Sciences, University of Nebraska-Lincoln, Lincoln, NE, 68510, USA.
F Joseph DaughertyPhenolics LLC, Omaha, NE, 68144, USA.
Michael S TempestaPhenolics LLC, Omaha, NE, 68144, USA.
Alekha K DashDepartment of Pharmacy Sciences, School of Pharmacy and Health Professions, Omaha, NE, 68178, USA.
Daniel J MuntDepartment of Pharmacy Sciences, School of Pharmacy and Health Professions, Omaha, NE, 68178, USA.
Richard J SchmidtDepartment of Nutrition and Human Sciences, University of Nebraska-Lincoln, Lincoln, NE, 68510, USA.
Glen O JohnsonDepartment of Nutrition and Human Sciences, University of Nebraska-Lincoln, Lincoln, NE, 68510, USA.
University of Nebraska–Lincoln · USUniversity of Nebraska at Omaha · USUniversity of South Alabama · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNumerous studies have demonstrated the efficacy of creatine supplementation for improvements in exercise performance. Few studies, however, have examined the effects of phosphocreatine supplementation on exercise performance. Furthermore, while polyphenols have antioxidant and anti-inflammatory properties, little is known regarding the influence of polyphenol supplementation on muscular strength, power, and endurance. Thus, the purpose of the present study was to compare the effects of 28 days of supplementation with phosphocreatine disodium salts plus blueberry extract (PCDSB), creatine monohydrate (CM), and placebo on measures of muscular strength, power, and endurance.

methodsThirty-three men were randomly assigned to consume either PCDSB, CM, or placebo for 28 days. Peak torque (PT), average power (AP), and percent decline for peak torque (PT%) and average power (AP%) were assessed from a fatigue test consisting of 50 maximal, unilateral, isokinetic leg extensions at 180°·s

resultsThe results demonstrated significant (p < 0.05) improvements in PT for the PCDSB and CM groups from pre- (99.90 ± 22.47 N·m and 99.95 ± 22.50 N·m, respectively) to post-supplementation (119.22 ± 29.87 N·m and 111.97 ± 24.50 N·m, respectively), but no significant (p = 0.112) change for the placebo group. The PCDSB and CM groups also exhibited significant improvements in AP from pre- (140.18 ± 32.08 W and 143.42 ± 33.84 W, respectively) to post-supplementation (170.12 ± 42.68 W and 159.78 ± 31.20 W, respectively), but no significant (p = 0.279) change for the placebo group. A significantly (p < 0.05) greater proportion of subjects in the PCDSB group exceeded the MID for PT compared to the placebo group, but there were no significant (p > 0.05) differences in the proportion of subjects exceeding the MID between the CM and placebo groups or between the CM and PCDSB groups.

conclusionsThese findings indicated that for the group mean responses, 28 days of supplementation with both PCDSB and CM resulted in increases in PT and AP. The PCDSB, however, may have an advantage over CM when compared to the placebo group for the proportion of individuals that respond favorably to supplementation with meaningful increases in muscular strength.

Indexed as

Blueberry PlantsCreatineDietary SupplementsDouble-Blind MethodHumansMaleMuscle, SkeletalMuscle StrengthPhosphocreatinePhysical EndurancePlant ExtractsTorqueYoung AdultCreatinePhosphocreatinePlant ExtractsAntioxidantBlueberryCreatine monohydrateIsokineticMuscular endurancePhosphocreatinePolyphenolsPowerStrength

Identifiers

PMID34503541
PMCPMC8427883
OpenAlexW3198299497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.