Evidence map›Paper›PMID 34503522›Full record

ArticleVirology journal2021

PAL1 gene of the phenylpropanoid pathway increases resistance to the Cassava brown streak virus in cassava.

Siji Kavil, Gerald Otti, Sophie Bouvaine, Andrew Armitage, Midatharahally N Maruthi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 36 citations in OpenAlex.

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  12. Frontiers in microbiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Siji KavilAgriculture, Health and Environment Department, Natural Resources Institute, University of Greenwich, Medway campus, Chatham, Kent, ME4 4TB, UK.
Gerald OttiAgriculture, Health and Environment Department, Natural Resources Institute, University of Greenwich, Medway campus, Chatham, Kent, ME4 4TB, UK.
Sophie BouvaineAgriculture, Health and Environment Department, Natural Resources Institute, University of Greenwich, Medway campus, Chatham, Kent, ME4 4TB, UK.
Andrew ArmitageAgriculture, Health and Environment Department, Natural Resources Institute, University of Greenwich, Medway campus, Chatham, Kent, ME4 4TB, UK.
Midatharahally N MaruthiAgriculture, Health and Environment Department, Natural Resources Institute, University of Greenwich, Medway campus, Chatham, Kent, ME4 4TB, UK. M.N.Maruthi@greenwich.ac.uk.ORCID 0000-0002-8060-866X
Natural Resources Institute · GBRothamsted Research · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe phenylalanine ammonia lyase genes play crucial role in plant response to biotic and abiotic stresses. In this study, we characterized the role of PAL genes in increasing resistance to the Cassava brown streak virus that causes the economically important cassava brown streak disease (CBSD) on cassava in Africa.

methodsThe whole transcriptomes of eight cassava varieties differing in resistance to CBSD were obtained at 1, 5 and 8 weeks after CBSV infection.

resultsAnalysis of RNA-Seq data identified the overexpression of PAL1, PAL2, cinnamic acid and two chalcone synthase genes in CBSD-resistant cassava varieties, which was subsequently confirmed by RT-qPCR. The exogenous application of Acibenzolar-S-Methyl induced PAL1 gene expression to enhance resistance in the susceptible var. Kalawe. In contrast, the silencing of PAL1 by RNA interference led to increased susceptibility of the resistant var. Kaleso to CBSD.

conclusionsPAL1 gene of the phenylpropanoid pathway has a major role in inducing resistance to CBSD in cassava plants and its early induction is key for CBSD resistance.

Indexed as

Disease ResistanceManihotPlant DiseasesPotyviridaeCassavaCBSDInductionPAL1Resistance

Identifiers

PMID34503522
PMCPMC8428094
OpenAlexW3198288375

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.