Observational studyBMC anesthesiology2021
The relationship between the effect-site concentration of propofol and sedation scale in children: a pharmacodynamic modeling study.
Observational study in BMC anesthesiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03195686 (Efficacy of PLEM100), which is not on this map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of PLEM100(Inbody®) to Measure the the Sedation Level in Pediatric Patients
Who cites it
3 citing papers in PubMed.
- Efficacy and Safety of Propofol as a Sole Sedative for fMRI Sedation in Autism Spectrum Disorder Individuals with Low IQ.Journal of autism and developmental disorders · 2026Article
- Utility of the Perfusion Index as an Indicator of Anesthetic Depth during Total Intravenous Anesthesia in Neurosurgery with Intraoperative Neuromonitoring : A Prospective Observational Study.Journal of Korean Neurosurgical Society · 2026Article
- Comparative Molecular Effects of Dexmedetomidine and Propofol on Osteoblast Migration and Osteogenic Gene Expression at Pediatric-Equivalent Concentrations: An In Vitro Study.Current issues in molecular biology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundContinuous infusion of propofol has been used to achieve sedation in children. However, the relationship between the effect-site concentration (C
methodsA total of 30 patients (aged 3 to 6 years) who underwent surgery under general anesthesia with propofol and remifentanil lasting more than 1 h were enrolled in this study. Sedation levels were evaluated using the UMSS score every 20 s by a 1 μg/mL stepwise increase in the C
resultsThe estimated C
conclusionsWe quantified the pharmacodynamic relationship between the C
trial registrationhttp://www.clinicaltrials.gov (No.: NCT03195686 , Date of registration: 22/06/2017).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.