Evidence map›Paper›PMID 34503319›Full record

ArticleThe Korean journal of internal medicine2021

Prevalence and characteristics of isolated nocturnal hypertension in the general population.

Moo-Yong Rhee, Je Sang Kim, Chee Hae Kim, Ji-Hyun Kim, Jung-Ha Lee, Sun-Woong Kim, Deuk-Young Nah, Namyi Gu, Eun-Joo Cho, Ki-Chul Sung and 1 more

Open access · goldAbstract read
In one paragraph

Article in The Korean journal of internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Isolated Nocturnal Hypertension in Children.Frontiers in pediatrics · 2022
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Moo-Yong RheeCardiovascular Center, Dongguk University Ilsan Hospital, Goyang, Korea.
Je Sang KimCardiovascular Center, Dongguk University Ilsan Hospital, Goyang, Korea.
Chee Hae KimCardiovascular Center, Dongguk University Ilsan Hospital, Goyang, Korea.
Ji-Hyun KimCardiovascular Center, Dongguk University Ilsan Hospital, Goyang, Korea.
Jung-Ha LeeCardiovascular Center, Dongguk University Ilsan Hospital, Goyang, Korea.
Sun-Woong KimDepartment of Statistics, Dongguk University, Seoul, Korea.
Deuk-Young NahCardiovascular Center, Dongguk University Gyeongju Hospital, Gyeongju, Korea.
Namyi GuDepartment of Clinical Pharmacology and Therapeutics, Dongguk University Ilsan Hospital, Goyang, Korea.
Eun-Joo ChoDepartment of Cardiology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Ki-Chul SungDepartment of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
Kyung-Soon HongDivision of Cardiology, Department of Internal Medicine, Hallym University College of Medicine, Chuncheon, Korea.
Dongguk University Ilsan Hospital · KRCatholic University of Korea · KRDongguk University · KRGyeongju University · KRHallym University · KRKangbuk Samsung Hospital · KR

Funding

Ministry of Food and Drug Safety 2011 (11162KFDA162), 2012 (12162MFDS103)
6 · The paper itself

Abstract

BACKGROUND/

aimsAscertaining the prevalence of isolated nocturnal hypertension (INHT) in the general population and identifying the characteristics of patients with INHT may be important to determine patients who should receive 24- hour ambulatory blood pressure (BP) measurements. This study aimed to evaluate the prevalence and characteristics of INHT in the general population.

methodsOf 1,128 participants (aged 20 to 70 years), we analyzed 823 who had valid 24-hour ambulatory BP measurements and were not on antihypertensive drug treatment.

resultsThe prevalence of INHT in the study was 22.8%. Individuals with INHT had a higher office, 24-hour, and daytime and nighttime ambulatory systolic and diastolic BPs compared to individuals with sustained day-night normotension. INHT was more prevalent in individuals with masked hypertension (MH) than in those with sustained hypertension (59.8% vs. 15.6%, p < 0.001). Among individuals with INHT, 92.6% had MH. Among individuals with office BP-based prehypertension, 34.5% had both INHT and MH. The prevalence of INHT was highest in individuals with office BP-based prehypertension. INHT was an independent determinant of MH after adjustment for age, sex, body mass index, diabetes, low-density-lipoprotein cholesterol, 24-hour systolic and diastolic BP, systolic and diastolic BP dipping, and systolic and diastolic BP non-dipping.

conclusionThe present study showed that INHT is not uncommon and is a major determinant of MH. Our findings strongly suggest the use of 24-hour ambulatory BP measurement for individuals within the prehypertension range of office BP owing to the high prevalence of INHT and MH in this population.

Indexed as

HypertensionMasked HypertensionBlood PressureBlood Pressure Monitoring, AmbulatoryCircadian RhythmHumansPrevalenceAmbulatory blood pressure monitoringMasked hypertensionNocturnalPrehypertension

Identifiers

PMID34503319
PMCPMC8435498
OpenAlexW3197727575

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.