Evidence map›Paper›PMID 34503276›Full record

ReviewCancers2021

The Race for Hydroxamate-Based Zirconium-89 Chelators.

Irene V J Feiner, Marie Brandt, Joseph Cowell, Tori Demuth, Daniëlle Vugts, Gilles Gasser, Thomas L Mindt

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Looking backward to move forward: a chemist's perspective on the future of radiopharmaceuticals.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2026
    Article
  8. The Evaluation of (1Molecules (Basel, Switzerland) · 2025
    Article
  9. Radiolabeling lipoproteins to study and manage disease.European journal of nuclear medicine and molecular imaging · 2025
    Review
  10. Article
  11. From Desferrioxamine B Umpolung to an Enantiopure Bifunctional Chelator forChemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  12. Towards DFO*Pharmaceutics · 2025
    Article
  13. Article
  14. Review
  15. Good practices forEJNMMI radiopharmacy and chemistry · 2024
    Review
  16. Article
  17. Article
  18. Preclinical Imaging of Prostate Cancer.Seminars in nuclear medicine · 2023
    Review
  19. Evaluation of Candidate Theranostics forJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  20. Toward OptimizedPharmaceutics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Irene V J FeinerLudwig Boltzmann Institute Applied Diagnostics, General Hospital of Vienna, 1090 Vienna, Austria.
Marie BrandtLudwig Boltzmann Institute Applied Diagnostics, General Hospital of Vienna, 1090 Vienna, Austria.
Joseph CowellInstitute of Chemistry for Life and Health Sciences, Laboratory for Inorganic Chemical Biology, Chimie ParisTech, PSL University, CNRS, 75005 Paris, France.ORCID 0000-0001-8750-7223
Tori DemuthTU Wien, Institut für Angewandte Synthesechemie, Getreidemarkt 9, 1060 Wien, Austria.
Daniëlle VugtsDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, VU University Amsterdam, 1081 HV Amsterdam, The Netherlands.
Gilles GasserInstitute of Chemistry for Life and Health Sciences, Laboratory for Inorganic Chemical Biology, Chimie ParisTech, PSL University, CNRS, 75005 Paris, France.ORCID 0000-0002-4244-5097
Thomas L MindtLudwig Boltzmann Institute Applied Diagnostics, General Hospital of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-2090-1725
Centre National de la Recherche Scientifique · FRLudwig Boltzmann Institute Applied Diagnostics · ATAmsterdam University Medical Centers · NLTU Wien · ATUniversity of Vienna · AT

Funding

Österreichische Forschungsförderungsgesellschaft 880630
6 · The paper itself

Abstract

Metallic radionuclides conjugated to biological vectors via an appropriate chelator are employed in nuclear medicine for the diagnosis (imaging) and radiotherapy of diseases. For the application of radiolabeled antibodies using positron emission tomography (immunoPET), zirconium-89 has gained increasing interest over the last decades as its physical properties (t

Indexed as

desferrioxamineDFOhydroxamate chelatorsimmunoPETzirconium-89

Identifiers

PMID34503276
PMCPMC8431476
OpenAlexW3197141120

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.