Evidence map›Paper›PMID 34503249›Full record

ReviewCancers2021

Leukoplakia in the Oral Cavity and Oral Microbiota: A Comprehensive Review.

Giacomo Pietrobon, Marta Tagliabue, Luigi Marco Stringa, Rita De Berardinis, Francesco Chu, Jacopo Zocchi, Elena Carlotto, Susanna Chiocca, Mohssen Ansarin

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 33 citations in OpenAlex.

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  6. Analysis ofF1000Research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Giacomo PietrobonDivision of Otolaryngology and Head and Neck Surgery, European Institute of Oncology IRCCS, 20142 Milan, Italy.
Marta TagliabueDivision of Otolaryngology and Head and Neck Surgery, European Institute of Oncology IRCCS, 20142 Milan, Italy.ORCID 0000-0002-7879-4846
Luigi Marco StringaUnit of Otolaryngology, University of Ferrara, 44121 Ferrara, Italy.
Rita De BerardinisDivision of Otolaryngology and Head and Neck Surgery, European Institute of Oncology IRCCS, 20142 Milan, Italy.ORCID 0000-0003-4959-587X
Francesco ChuDivision of Otolaryngology and Head and Neck Surgery, European Institute of Oncology IRCCS, 20142 Milan, Italy.
Jacopo ZocchiDivision of Otolaryngology and Head and Neck Surgery, European Institute of Oncology IRCCS, 20142 Milan, Italy.
Elena CarlottoDepartment of Otorhinolaryngology, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Susanna ChioccaDepartment of Experimental Oncology, European Institute of Oncology IRCCS, 20139 Milan, Italy.ORCID 0000-0002-9721-0850
Mohssen AnsarinDivision of Otolaryngology and Head and Neck Surgery, European Institute of Oncology IRCCS, 20142 Milan, Italy.
European Institute of Oncology · ITPoliclinico San Matteo Fondazione · ITUniversity of Ferrara · ITUniversity of Sassari · IT

Funding

Ministero della Salute Ricerca Corrente and 5x1000 funds.
6 · The paper itself

Abstract

We reviewed the current published literature on the impact of oral microbiota on oral cavity leukoplakia (OLK), aiming at clarifying its role in disease transformation. The analysis unveiled that bacterial richness and diversity in the oral cavity tend to be decreased in OLK compared to healthy controls, with a reduction in the prevalent commensals, such as

Indexed as

dysplasiamicrobiomemicrobiotaoral cavity canceroral cavity leukoplakiapremalignant disorder

Identifiers

PMID34503249
PMCPMC8431082
OpenAlexW3196951764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.