Evidence map›Paper›PMID 34503175›Full record

ArticleCancers2021

miR-22 Modulates Lenalidomide Activity by Counteracting MYC Addiction in Multiple Myeloma.

Daniele Caracciolo, Caterina Riillo, Giada Juli, Francesca Scionti, Katia Todoerti, Nicoletta Polerà, Katia Grillone, Lucia Fiorillo, Mariamena Arbitrio, Maria Teresa Di Martino and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
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  5. The FGF/FGFR/c-Myc axis as a promising therapeutic target in multiple myeloma.Journal of experimental & clinical cancer research : CR · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Daniele CaraccioloDepartment of Experimental and Clinical Medicine, Magna Græcia University, 88100 Catanzaro, Italy.
Caterina RiilloDepartment of Experimental and Clinical Medicine, Magna Græcia University, 88100 Catanzaro, Italy.ORCID 0000-0002-7983-5099
Giada JuliDepartment of Experimental and Clinical Medicine, Magna Græcia University, 88100 Catanzaro, Italy.
Francesca SciontiInstitute of Research and Biomedical Innovation (IRIB), Italian National Council (CNR), 98164 Messina, Italy.
Katia TodoertiHematology, Fondazione Cà Granda IRCCS Policlinico, 20019 Milan, Italy.
Nicoletta PoleràDepartment of Experimental and Clinical Medicine, Magna Græcia University, 88100 Catanzaro, Italy.
Katia GrilloneDepartment of Experimental and Clinical Medicine, Magna Græcia University, 88100 Catanzaro, Italy.ORCID 0000-0003-0268-5536
Lucia FiorilloDepartment of Experimental and Clinical Medicine, Magna Græcia University, 88100 Catanzaro, Italy.
Mariamena ArbitrioInstitute of Research and Biomedical Innovation (IRIB), Italian National Council (CNR), 88100 Catanzaro, Italy.
Maria Teresa Di MartinoDepartment of Experimental and Clinical Medicine, Magna Græcia University, 88100 Catanzaro, Italy.ORCID 0000-0002-8205-2706
Antonino NeriHematology, Fondazione Cà Granda IRCCS Policlinico, 20019 Milan, Italy.
Pierosandro TagliaferriDepartment of Experimental and Clinical Medicine, Magna Græcia University, 88100 Catanzaro, Italy.
Pierfrancesco TassoneDepartment of Experimental and Clinical Medicine, Magna Græcia University, 88100 Catanzaro, Italy.
Magna Graecia University · ITInstitute for Biomedical Research and Innovation · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of Milan · IT

Funding

AIRC 21588Associazione Italiana per la Ricerca sul Cancro 16695
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

lenalidomidemicroRNAmiR-22multiple myelomaMYCNK cells

Identifiers

PMID34503175
PMCPMC8431372
OpenAlexW3196717417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.