Evidence map›Paper›PMID 34503124›Full record

ArticleCancers2021

Impact of Adjuvant Radiotherapy in Patients with Central Neurocytoma: A Multicentric International Analysis.

Laith Samhouri, Mohamed A M Meheissen, Ahmad K H Ibrahimi, Abdelatif Al-Mousa, Momen Zeineddin, Yasser Elkerm, Zeyad M A Hassanein, Abdelsalam Attia Ismail, Hazem Elmansy, Motasem M Al-Hanaqta and 7 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 3 countries.

Laith SamhouriDepartment of Radiation Oncology, University Hospital Münster, Münster 48149, Germany.
Mohamed A M MeheissenAlexandria Clinical Oncology Department, Alexandria University, Alexandria 21500, Egypt.ORCID 0000-0002-2514-4727
Ahmad K H IbrahimiDepartment of Radiotherapy and Radiation Oncology, King Hussein Cancer Center, Amman 11942, Jordan.
Abdelatif Al-MousaDepartment of Radiotherapy and Radiation Oncology, King Hussein Cancer Center, Amman 11942, Jordan.
Momen ZeineddinDepartment of Pediatrics, King Hussein Cancer Center, Amman 11942, Jordan.
Yasser ElkermSpecialized Universal Network of Oncology (SUN), Alexandria 21500, Egypt.
Zeyad M A HassaneinAlexandria Clinical Oncology Department, Alexandria University, Alexandria 21500, Egypt.ORCID 0000-0003-2961-9512
Abdelsalam Attia IsmailAlexandria Clinical Oncology Department, Alexandria University, Alexandria 21500, Egypt.
Hazem ElmansySpecialized Universal Network of Oncology (SUN), Alexandria 21500, Egypt.
Motasem M Al-HanaqtaMilitary Oncology Center, Royal Medical Services, Amman 11942, Jordan.ORCID 0000-0003-2004-2892
Omar A Al-AzzamPrincess Iman Research Center, King Hussein Medical Center, Royal Medical Services, Amman 11942, Jordan.
Amr Abdelaziz ElsaidAlexandria Clinical Oncology Department, Alexandria University, Alexandria 21500, Egypt.ORCID 0000-0003-0264-1744
Christopher KittelDepartment of Radiation Oncology, University Hospital Münster, Münster 48149, Germany.
Oliver MickeDepartment of Radiotherapy and Radiation Oncology, Franziskus Hospital Bielefeld, 33699 Bielefeld, Germany.
Walter StummerDepartment of Neurosurgery, University Hospital Münster, 48149 Münster, Germany.
Khaled ElsayadDepartment of Radiation Oncology, University Hospital Münster, Münster 48149, Germany.ORCID 0000-0001-9303-7336
Hans Theodor EichDepartment of Radiation Oncology, University Hospital Münster, Münster 48149, Germany.
Alexandria University · EGUniversity Hospital Münster · DEKing Hussein Cancer Center · JOKing Hussein Medical Center · JOFrancis Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCentral neurocytoma (CN) is a rare tumor accounting for <0.5% of all intracranial tumors. Surgery ± radiotherapy is the mainstay treatment. This international multicentric study aims to evaluate the outcomes of CNs patients after multimodal therapies and identify predictive factors. PATIENTS AND

methodsWe retrospectively identified 33 patients with CN treated between 2005 and 2019. Treatment characteristics and outcomes were assessed.

resultsAll patients with CN underwent surgical resection. Radiotherapy was delivered in 19 patients. The median radiation dose was 54 Gy (range, 50-60 Gy). The median follow-up time was 56 months. The 5-year OS and 5-year PFS were 90% and 76%, respectively. Patients who received radiotherapy had a significantly longer PFS than patients without RT (

conclusionsUsing RT seems to be associated with longer survival rates with an acceptable toxicity profile.

Indexed as

managementneurocytomaradiation therapyrare tumorstoxicities

Identifiers

PMID34503124
PMCPMC8430823
OpenAlexW3193994607

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.