Evidence map›Paper›PMID 34503105›Full record

ArticleCancers2021

Immune-Omics Networks of

Qing Ye, Salvi Singh, Peter R Qian, Nancy Lan Guo

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Fresh Insights IntoOncology reviews · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Qing YeWest Virginia University Cancer Institute, West Virginia University, Morgantown, WV 26506, USA.
Salvi SinghWest Virginia University Cancer Institute, West Virginia University, Morgantown, WV 26506, USA.
Peter R QianWest Virginia University Cancer Institute, West Virginia University, Morgantown, WV 26506, USA.
Nancy Lan GuoWest Virginia University Cancer Institute, West Virginia University, Morgantown, WV 26506, USA.ORCID 0000-0002-8050-6268
West Virginia University · US

Funding

NIH HHS R01/R56LM009500Office of Extramural Research, National Institutes of Health NIGMS/XLerateHealth LLC (4UT2GM130174)Office of Extramural Research, National Institutes of Health P20RR16440 and ARRA Supplement
6 · The paper itself

Abstract

To date, there are no prognostic/predictive biomarkers to select chemotherapy, immunotherapy, and radiotherapy in individual non-small cell lung cancer (NSCLC) patients. Major immune-checkpoint inhibitors (ICIs) have more DNA copy number variations (CNV) than mutations in The Cancer Genome Atlas (TCGA) NSCLC tumors. Nevertheless, CNV-mediated dysregulated gene expression in NSCLC is not well understood. Integrated CNV and transcriptional profiles in NSCLC tumors (

Indexed as

biomarkersBoolean implication networkschemotherapyCRISPR-Cas9DNA copy number variationimmunotherapynon-small cell lung cancer (NSCLC)radiotherapyrepurposing drugsRNA interference (RNAi)

Identifiers

PMID34503105
PMCPMC8428355
OpenAlexW3196899630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.