Evidence map›Paper›PMID 34503090›Full record

ArticleCancers2021

An Improved Animal Model of Multiple Myeloma Bone Disease.

Syed Hassan Mehdi, Carol A Morris, Jung Ae Lee, Donghoon Yoon

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Syed Hassan MehdiMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Carol A MorrisGraduate Program in Interdisciplinary Biomedical Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Jung Ae LeeDepartment of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Donghoon YoonMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
University of Arkansas for Medical Sciences · USUniversity of Massachusetts Chan Medical School · US

Funding

Understanding the Negative Prognostic Impact of Intraosseous Focal Lesions in Multiple MyelomaP20GM125503 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI CHARLES A O'BRIEN · 2018 to 2026
$23.0M
In situ imaging of collagen degradation activity in multiple myeloma and lung fibrosis mouse modelR21OD026618 · OD · UNIVERSITY OF UTAH · PI YOON, DONGHOON, YU, MICHAEL S · 2019 to 2020
$430k
NIGMS NIH HHS P20 GM125503NIH HHS R21 OD026618
6 · The paper itself

Abstract

Multiple myeloma (MM) is a plasma cell malignancy that causes an accumulation of terminally differentiated monoclonal plasma cells in the bone marrow, accompanied by multiple myeloma bone disease (MMBD). MM animal models have been developed and enable to interrogate the mechanism of MM tumorigenesis. However, these models demonstrate little or no evidence of MMBD. We try to establish the MMBD model with severe bone lesions and easily accessible MM progression. 1 × 10

Indexed as

multiple myeloma bone diseasemurine modelsevere osteolytic lesions

Identifiers

PMID34503090
PMCPMC8428359
OpenAlexW3194385036

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.