Evidence map›Paper›PMID 34503043›Full record

ArticlePolymers2021

New Approach toward Laser-Assisted Modification of Biocompatible Polymers Relevant to Neural Interfacing Technologies.

Nadya Stankova, Anastas Nikolov, Ekaterina Iordanova, Georgi Yankov, Nikolay Nedyalkov, Petar Atanasov, Dragomir Tatchev, Eugenia Valova, Konstantin Kolev, Stephan Armyanov and 2 more

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Nadya StankovaInstitute of Electronics, Bulgarian Academy of Sciences, 72 Tzarigradsko Shousse Blvd., 1784 Sofia, Bulgaria.
Anastas NikolovInstitute of Electronics, Bulgarian Academy of Sciences, 72 Tzarigradsko Shousse Blvd., 1784 Sofia, Bulgaria.
Ekaterina IordanovaInstitute of Solid State Physics, Bulgarian Academy of Sciences, 72 Tzarigradsko Shousse Blvd., 1784 Sofia, Bulgaria.
Georgi YankovInstitute of Solid State Physics, Bulgarian Academy of Sciences, 72 Tzarigradsko Shousse Blvd., 1784 Sofia, Bulgaria.
Nikolay NedyalkovInstitute of Electronics, Bulgarian Academy of Sciences, 72 Tzarigradsko Shousse Blvd., 1784 Sofia, Bulgaria.
Petar AtanasovInstitute of Electronics, Bulgarian Academy of Sciences, 72 Tzarigradsko Shousse Blvd., 1784 Sofia, Bulgaria.
Dragomir TatchevInstitute of Physical Chemistry, Bulgarian Academy of Sciences, Acad. Georgi Bonchev Str. Bld.11, 1113 Sofia, Bulgaria.
Eugenia ValovaInstitute of Physical Chemistry, Bulgarian Academy of Sciences, Acad. Georgi Bonchev Str. Bld.11, 1113 Sofia, Bulgaria.
Konstantin KolevInstitute of Physical Chemistry, Bulgarian Academy of Sciences, Acad. Georgi Bonchev Str. Bld.11, 1113 Sofia, Bulgaria.
Stephan ArmyanovInstitute of Physical Chemistry, Bulgarian Academy of Sciences, Acad. Georgi Bonchev Str. Bld.11, 1113 Sofia, Bulgaria.
Daniela KarashanovaInstitute of Optical Materials and Technologies, Bulgarian Academy of Sciences, G. Bonchev Street, Bl. 109, 1113 Sofia, Bulgaria.ORCID 0000-0002-8785-3190
Naoki FukataInternational Center for Materials for Nanoarchitectonics (MANA), National Institute for Materials Science (NIMS), 1-1Namiki, Tsikuba 305-0044, Japan.
Bulgarian Academy of Sciences · BGNational Institute for Materials Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report on a new approach toward a laser-assisted modification of biocompatible polydimethylsiloxane (PDMS) elastomers relevant to the fabrication of stretchable multielectrode arrays (MEAs) devices for neural interfacing technologies. These applications require high-density electrode packaging to provide a high-resolution integrating system for neural stimulation and/or recording. Medical grade PDMS elastomers are highly flexible with low Young's modulus < 1 MPa, which are similar to soft tissue (nerve, brain, muscles) among the other known biopolymers, and can easily adjust to the soft tissue curvatures. This property ensures tight contact between the electrodes and tissue and promotes intensive development of PDMS-based MEAs interfacing devices in the basic neuroscience, neural prosthetics, and hybrid bionic systems, connecting the human nervous system with electronic or robotic prostheses for restoring and treating neurological diseases. By using the UV harmonics 266 and 355 nm of Nd:YAG laser medical grade PDMS elastomer is modified by ns-laser ablation in water. A new approach of processing is proposed to (i) activate the surface and to obtain tracks with (ii) symmetric U-shaped profiles and (iii) homogeneous microstructure This technology provides miniaturization of the device and successful functionalization by electroless metallization of the tracks with platinum (Pt) without preliminary sensitization by tin (Sn) and chemical activation by palladium (Pd). As a result, platinum black layers with a cauliflower-like structure with low values of sheet resistance between 1 and 8 Ω/sq are obtained.

Indexed as

electroless metallizationimplantsneural interfacing technologiesns-laser ablation in waterPDMS polymerplatinum Pt black

Identifiers

PMID34503043
PMCPMC8433805
OpenAlexW3197086898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.