Evidence map›Paper›PMID 34502551›Full record

ReviewInternational journal of molecular sciences2021

JNK Signaling in

Tian Gan, Lixia Fan, Long Zhao, Mala Misra, Min Liu, Min Zhang, Ying Su

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

  1. International journal of molecular sciences · 2026
    Review
  2. Article
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  15. International journal of molecular sciences · 2024
    Review
  16. Special Issue: MAPK Signaling Cascades in Human Health and Diseases.International journal of molecular sciences · 2024
    Article
  17. Article
  18. c-Jun N-terminal kinase signaling in aging.Frontiers in aging neuroscience · 2024
    Review
  19. Branched-Chain Amino Acid Accumulation Fuels the Senescence-Associated Secretory Phenotype.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  20. JNK Cascade-Induced Apoptosis-A Unique Role in GqPCR Signaling.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Tian GanInstitute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao 266003, China.
Lixia FanInstitute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao 266003, China.
Long ZhaoInstitute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao 266003, China.
Mala MisraDepartment of Biology, Washington College, Chestertown, MD 21620, USA.
Min LiuMinistry of Education Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences, Peking University, Beijing 100871, China.ORCID 0000-0002-8077-0130
Min ZhangDivision of Biomedical Sciences, University of California, Riverside, CA 92521, USA.
Ying SuInstitute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao 266003, China.ORCID 0000-0002-8466-0043
Ministry of Education of the People's Republic of China · CNOcean University of China · CNPeking University · CNUniversity of California, Riverside · USWashington College · US

Funding

Fundamental Research Funds for Central Universities, China 202012004National Natural Science Foundation of China 31970475National Natural Science Foundation of China 31970506
6 · The paper itself

Abstract

The evolutionarily conserved c-Jun N-terminal kinase (JNK) signaling pathway is a critical genetic determinant in the control of longevity. In response to extrinsic and intrinsic stresses, JNK signaling is activated to protect cells from stress damage and promote survival. In

Indexed as

AgingAnimalsBrainDrosophila melanogasterDrosophila ProteinsFat BodyJNK Mitogen-Activated Protein KinasesLongevityMAP Kinase Signaling SystemModels, BiologicalNeuronsbsk protein, DrosophilaDrosophila ProteinsJNK Mitogen-Activated Protein KinasesagingDrosophilaJNKlifespan

Identifiers

PMID34502551
PMCPMC8431792
OpenAlexW3196371443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.