Evidence map›Paper›PMID 34502490›Full record

ReviewInternational journal of molecular sciences2021

CD4

Yi-Hsing Chen, Sue Lightman, Virginia L Calder

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Comparative models of uveitis.Eye (London, England) · 2025
    Review
  4. Article
  5. Article
  6. Role of CD4Clinical and experimental medicine · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Enriched and Decreased Intestinal Microbes in Active VKH Patients.Investigative ophthalmology & visual science · 2022
    Article
  16. Grand Challenges in Ocular Inflammatory Diseases.Frontiers in ophthalmology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Yi-Hsing ChenUCL Institute of Ophthalmology, University College London, London EC1V 9EL, UK.
Sue LightmanUCL Institute of Ophthalmology, University College London, London EC1V 9EL, UK.
Virginia L CalderUCL Institute of Ophthalmology, University College London, London EC1V 9EL, UK.
Chang Gung University · TWMoorfields Eye Hospital NHS Foundation Trust · GBUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-infectious uveitis (NIU) is a potentially sight-threatening disease. Effector CD4

Indexed as

AnimalsCD4-Positive T-LymphocytesCell PlasticityHumansInflammationInterleukin-10Interleukin-17Retinal DiseasesIL10 protein, humanInterleukin-10Interleukin-17CD4+ T cell plasticityexperimental autoimmune uveitisregulatory (Treg) T cellsTh17 cellsTh17/Th1 (CD4+IFNγ+IL-17+) cellsTh17/Treg (CD4+IL-17+FoxP3+) cellsTh1 cellsuveitis

Identifiers

PMID34502490
PMCPMC8431487
OpenAlexW3198668715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.