Evidence map›Paper›PMID 34502444›Full record

ArticleInternational journal of molecular sciences2021

Oligomeric and Fibrillar Species of Aβ42 Diversely Affect Human Neural Stem Cells.

Adela Bernabeu-Zornoza, Raquel Coronel, Charlotte Palmer, Victoria López-Alonso, Isabel Liste

Open access · goldAbstract readComparative Study
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. [Sulforaphane reduces reactive astrocyte-mediated neuron apoptosisNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Adela Bernabeu-ZornozaUnidad de Regeneración Neural, Unidad Funcional de Investigación de Enfermedades Crónicas (UFIEC), Instituto de Salud Carlos III (ISCIII), Majadahonda, 28220 Madrid, Spain.ORCID 0000-0001-6238-1791
Raquel CoronelUnidad de Regeneración Neural, Unidad Funcional de Investigación de Enfermedades Crónicas (UFIEC), Instituto de Salud Carlos III (ISCIII), Majadahonda, 28220 Madrid, Spain.
Charlotte PalmerUnidad de Regeneración Neural, Unidad Funcional de Investigación de Enfermedades Crónicas (UFIEC), Instituto de Salud Carlos III (ISCIII), Majadahonda, 28220 Madrid, Spain.
Victoria López-AlonsoUnidad de Biología Computacional, Unidad Funcional de Investigación de Enfermedades Crónicas (UFIEC), Instituto de Salud Carlos III (ISCIII), Majadahonda, 28220 Madrid, Spain.ORCID 0000-0001-8129-8352
Isabel ListeUnidad de Regeneración Neural, Unidad Funcional de Investigación de Enfermedades Crónicas (UFIEC), Instituto de Salud Carlos III (ISCIII), Majadahonda, 28220 Madrid, Spain.
Instituto de Salud Carlos III · ES

Funding

Comunidad de Madrid NEUROSTEMCM consortium; S2010/BMD-2336MICINN-ISCIII PI-10/00291 and MPY1412/09MINECO SAF2015-71140-RSpanish Ministry of Science and Innovation RTI2018-101663-B-100
6 · The paper itself

Abstract

Amyloid-β 42 peptide (Aβ

Indexed as

Amyloid beta-PeptidesHumansNeural Stem CellsPeptide FragmentsPrimary Cell CultureAmyloid beta-Peptidesamyloid beta-protein (1-42)Peptide FragmentsAlzheimer’sAβ42Aβ peptidecell deathcell differentiationfibrilshuman NSCsoligomers

Identifiers

PMID34502444
PMCPMC8430695
OpenAlexW3197885294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.