Evidence map›Paper›PMID 34502434›Full record

ArticleInternational journal of molecular sciences2021

αV Integrin Expression and Localization in Male Germ Cells.

Veronika Palenikova, Michaela Frolikova, Eliska Valaskova, Pavla Postlerova, Katerina Komrskova

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Role of Integrins in Sperm Activation and Fertilization.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Veronika PalenikovaLaboratory of Reproductive Biology, Institute of Biotechnology of the Czech Academy of Sciences, BIOCEV, Prumyslova 595, 252 50 Vestec, Czech Republic.
Michaela FrolikovaLaboratory of Reproductive Biology, Institute of Biotechnology of the Czech Academy of Sciences, BIOCEV, Prumyslova 595, 252 50 Vestec, Czech Republic.ORCID 0000-0002-9834-8405
Eliska ValaskovaLaboratory of Reproductive Biology, Institute of Biotechnology of the Czech Academy of Sciences, BIOCEV, Prumyslova 595, 252 50 Vestec, Czech Republic.
Pavla PostlerovaLaboratory of Reproductive Biology, Institute of Biotechnology of the Czech Academy of Sciences, BIOCEV, Prumyslova 595, 252 50 Vestec, Czech Republic.ORCID 0000-0002-5090-4652
Katerina KomrskovaLaboratory of Reproductive Biology, Institute of Biotechnology of the Czech Academy of Sciences, BIOCEV, Prumyslova 595, 252 50 Vestec, Czech Republic.ORCID 0000-0002-6837-2148
Charles University · CZCzech Academy of Sciences, Institute of Biotechnology · CZCzech University of Life Sciences Prague · CZ

Funding

BIOCEV CZ.1.05/1.1.00/02.0109Czech Education and Scientific NETwork-CESNET LM2015042Grantová Agentura České Republiky GC20-20217JGrantová Agentura, Univerzita Karlova 1408120Institute of Biotechnology of the Czech Academy of Sciences RVO 86652036Institutional support from the Czech-BioImaging CZ.02.1.01/0.0/0.0/16_013/0001775Institutional support from the Czech-BioImaging LM2015062MEYS CZ.02.1.01/0.0/0.0/16_013/0001775MEYS LM2015062MEYS LO1419Operational Program Prague Competitiveness CZ.2.16/3.1.00/21515OPPK CZ.2.16/3.1.00/21547
6 · The paper itself

Abstract

Integrins are transmembrane receptors that facilitate cell adhesion and cell-extracellular matrix communication. They are involved in the sperm maturation including capacitation and gamete interaction, resulting in successful fertilization. αV integrin belongs to the integrin glycoprotein superfamily, and it is indispensable for physiological spermiogenesis and testosterone production. We targeted the gene and protein expression of the αV integrin subunit and described its membrane localization in sperm. Firstly, in mouse, we traced

Indexed as

Acrosome ReactionAnimalsHumansIntegrin alphaVMaleMiceSpermatozoaSwineIntegrin alphaVhumanmale germ cellsmousepigspermαV integrin

Identifiers

PMID34502434
PMCPMC8431249
OpenAlexW3196718694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.