Evidence map›Paper›PMID 34502419›Full record

ArticleInternational journal of molecular sciences2021

Follistatin-Like-1 (FSTL1) Is a Fibroblast-Derived Growth Factor That Contributes to Progression of Chronic Kidney Disease.

Nicholas A Maksimowski, Xuewen Song, Eun Hui Bae, Heather Reich, Rohan John, York Pei, James W Scholey, Nephrotic Syndrome Study Network Neptune

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nicholas A MaksimowskiInstitute of Medical Science, University of Toronto, Toronto, ON M5S 1A8, Canada.
Xuewen SongDivision of Nephrology, University Health Network, Toronto, ON M5G 2C4, Canada.
Eun Hui BaeDepartments of Internal Medicine, Chonnam National University Medical School, Gwangju 61469, Korea.ORCID 0000-0003-1727-2822
Heather ReichDivision of Nephrology, University Health Network, Toronto, ON M5G 2C4, Canada.
Rohan JohnToronto General Hospital Research Institute, University Health Network, Toronto, ON M5G 2C4, Canada.
York PeiInstitute of Medical Science, University of Toronto, Toronto, ON M5S 1A8, Canada.
James W ScholeyInstitute of Medical Science, University of Toronto, Toronto, ON M5S 1A8, Canada.
Nephrotic Syndrome Study Network Neptune

Funding

Training Program in Clinical & Translationa Research in Human Glomerular DiseaseU54DK083912 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GIPSON, DEBBIE S · 2009 to 2023
$20.3M
NIDDK NIH HHS U54 DK083912
6 · The paper itself

Abstract

Our understanding of the mechanisms responsible for the progression of chronic kidney disease (CKD) is incomplete. Microarray analysis of kidneys at 4 and 7 weeks of age in

Indexed as

AnimalsCollagen Type ICollagen Type I, alpha 1 ChainDisease Models, AnimalDisease ProgressionFibroblast Growth FactorsFollistatin-Related ProteinsMiceMice, KnockoutNuclear ProteinsRenal Insufficiency, ChronicToll-Like Receptor 4Collagen Type ICollagen Type I, alpha 1 ChainDip2a protein, mouseFibroblast Growth FactorsFollistatin-Related ProteinsFstl1 protein, mouseNuclear ProteinsTlr4 protein, mouseToll-Like Receptor 4apoptosiscytokinesfibrosisFSTL1inflammationkidneynephrotic syndrome

Identifiers

PMID34502419
PMCPMC8431028

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.