Evidence map›Paper›PMID 34502400›Full record

ArticleInternational journal of molecular sciences2021

Multilevel Approach for the Treatment of Giardiasis by Targeting Arginine Deiminase.

Cynthia Fernández-Lainez, Ignacio de la Mora-de la Mora, Itzhel García-Torres, Sergio Enríquez-Flores, Luis A Flores-López, Pedro Gutiérrez-Castrellón, Lilian Yépez-Mulia, Felix Matadamas-Martínez, Paul de Vos, Gabriel López-Velázquez

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Repurposing of rabeprazole as an anti-Journal of enzyme inhibition and medicinal chemistry · 2023
    Article
  4. The Giardial Arginine Deiminase Participates inInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Cynthia Fernández-LainezLaboratorio de Errores Innatos del Metabolismo y Tamiz, Instituto Nacional de Pediatría, Ciudad de Mexico 04530, Mexico.ORCID 0000-0001-7468-3420
Ignacio de la Mora-de la MoraLaboratorio de Biomoléculas y Salud Infantil, Instituto Nacional de Pediatría, Ciudad de Mexico 04530, Mexico.ORCID 0000-0002-5654-8089
Itzhel García-TorresLaboratorio de Biomoléculas y Salud Infantil, Instituto Nacional de Pediatría, Ciudad de Mexico 04530, Mexico.ORCID 0000-0002-3018-060X
Sergio Enríquez-FloresLaboratorio de Biomoléculas y Salud Infantil, Instituto Nacional de Pediatría, Ciudad de Mexico 04530, Mexico.ORCID 0000-0003-2058-5707
Luis A Flores-LópezLaboratorio de Biomoléculas y Salud Infantil, Instituto Nacional de Pediatría, Ciudad de Mexico 04530, Mexico.
Pedro Gutiérrez-CastrellónHospital General Dr. Manuel Gea González, Ciudad de Mexico 14080, Mexico.ORCID 0000-0002-9885-9635
Lilian Yépez-MuliaUnidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, UMAE Hospital de Pediatría, Centro Médico Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de Mexico 06720, Mexico.ORCID 0000-0001-8675-5671
Felix Matadamas-MartínezUnidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, UMAE Hospital de Pediatría, Centro Médico Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de Mexico 06720, Mexico.
Paul de VosImmunoendocrinology, Division of Medical Biology, Department of Pathology and Medical Biology, University of Groningen and University Medical Centre Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands.ORCID 0000-0001-9618-2408
Gabriel López-VelázquezLaboratorio de Biomoléculas y Salud Infantil, Instituto Nacional de Pediatría, Ciudad de Mexico 04530, Mexico.ORCID 0000-0003-4664-2722
Instituto Nacional de Pediatria · MXMexican Social Security Institute · MXUniversity Medical Center Groningen · NLHospital General Dr. Manuel Gea Gonzalez · MXSecretaria de Salud · MX

Funding

Instituto Nacional de Pediatria 2019/062
6 · The paper itself

Abstract

Giardiasis represents a latent problem in public health due to the exceptionally pathogenic strategies of the parasite

Indexed as

AnimalsAntiprotozoal AgentsComputer SimulationCysteineDrug Evaluation, PreclinicalDrug RepositioningGiardia lambliaGiardiasisGold Sodium ThiomalateHumansHydrolasesOmeprazoleProton Pump InhibitorsRabeprazoleThiamineTrophozoitesAntiprotozoal Agentsarginine deiminaseCysteineGold Sodium ThiomalateHydrolasesOmeprazoleProton Pump InhibitorsRabeprazolesulbutiamineThiamineaurothiomalatedrug repurposingGiardiaomeprazoleproton pump inhibitorrabeprazolesulbutiamine

Identifiers

PMID34502400
PMCPMC8431557
OpenAlexW3198533834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.