Evidence map›Paper›PMID 34502340›Full record

ArticleInternational journal of molecular sciences2021

Development of Effective Therapeutic Molecule from Natural Sources against Coronavirus Protease.

Adewale Oluwaseun Fadaka, Nicole Remaliah Samantha Sibuyi, Darius Riziki Martin, Ashwil Klein, Abram Madiehe, Mervin Meyer

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  4. Review
  5. Article
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  7. Review
  8. Article
  9. Bridging the Chemical Profile and Biological Activities of a New Variety ofInternational journal of molecular sciences · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Adewale Oluwaseun FadakaDepartment of Science and Innovation/Mintek Nanotechnology Innovation Centre, Biolabels Node, Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Bellville, Cape Town 7535, South Africa.ORCID 0000-0002-3952-2098
Nicole Remaliah Samantha SibuyiDepartment of Science and Innovation/Mintek Nanotechnology Innovation Centre, Biolabels Node, Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Bellville, Cape Town 7535, South Africa.ORCID 0000-0001-7175-5388
Darius Riziki MartinDepartment of Science and Innovation/Mintek Nanotechnology Innovation Centre, Biolabels Node, Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Bellville, Cape Town 7535, South Africa.ORCID 0000-0001-8673-1581
Ashwil KleinPlant Omics Laboratory, Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Private Bag X17, Bellville, Cape Town 7535, South Africa.ORCID 0000-0002-5606-886X
Abram MadieheDepartment of Science and Innovation/Mintek Nanotechnology Innovation Centre, Biolabels Node, Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Bellville, Cape Town 7535, South Africa.ORCID 0000-0002-3935-467X
Mervin MeyerDepartment of Science and Innovation/Mintek Nanotechnology Innovation Centre, Biolabels Node, Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Bellville, Cape Town 7535, South Africa.ORCID 0000-0002-8296-4860

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The SARS-CoV-2 main protease (M

Indexed as

Binding SitesBiological ProductsCatalytic DomainCoronavirus M ProteinsCOVID-19COVID-19 Drug TreatmentDrug DesignHumansLigandsMolecular Docking SimulationMolecular Dynamics SimulationProtease InhibitorsQuercetinSARS-CoV-2Viral Matrix ProteinsBiological ProductsCoronavirus M ProteinsLigandsmembrane protein, SARS-CoV-2Protease InhibitorsQuercetinquercetin-3-O-neohesperidoseViral Matrix Proteinsantiviral agentsCOVID-19dockingflavonolsin silico approachMDsMM/GBSAMpronatural productsprotein-ligand interactionSARS-CoV-2

Identifiers

PMID34502340
PMCPMC8430653

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.