Evidence map›Paper›PMID 34502252›Full record

ArticleInternational journal of molecular sciences2021

Hydration of Simple Model Peptides in Aqueous Osmolyte Solutions.

Aneta Panuszko, Maciej Pieloszczyk, Anna Kuffel, Karol Jacek, Karol A Biernacki, Sebastian Demkowicz, Janusz Stangret, Piotr Bruździak

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Hydration ofMolecules (Basel, Switzerland) · 2024
    Article
  4. Amide Spectral Fingerprints are Hydrogen Bonding-Mediated.The journal of physical chemistry letters · 2022
    Article
  5. Article
  6. Article
  7. Taurine Stabilizing Effect on Lysozyme.Life (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Aneta PanuszkoDepartment of Physical Chemistry, Gdańsk University of Technology, Narutowicza 11/12, 80-233 Gdańsk, Poland.ORCID 0000-0002-4653-0010
Maciej PieloszczykDepartment of Physical Chemistry, Gdańsk University of Technology, Narutowicza 11/12, 80-233 Gdańsk, Poland.
Anna KuffelDepartment of Physical Chemistry, Gdańsk University of Technology, Narutowicza 11/12, 80-233 Gdańsk, Poland.ORCID 0000-0003-2078-4220
Karol JacekDepartment of Physical Chemistry, Gdańsk University of Technology, Narutowicza 11/12, 80-233 Gdańsk, Poland.ORCID 0000-0002-8698-9934
Karol A BiernackiDepartment of Organic Chemistry, Gdańsk University of Technology, Narutowicza 11/12, 80-233 Gdańsk, Poland.ORCID 0000-0003-3036-8693
Sebastian DemkowiczDepartment of Organic Chemistry, Gdańsk University of Technology, Narutowicza 11/12, 80-233 Gdańsk, Poland.ORCID 0000-0002-4252-4297
Janusz StangretDepartment of Physical Chemistry, Gdańsk University of Technology, Narutowicza 11/12, 80-233 Gdańsk, Poland.ORCID 0000-0002-9852-4747
Piotr BruździakDepartment of Physical Chemistry, Gdańsk University of Technology, Narutowicza 11/12, 80-233 Gdańsk, Poland.ORCID 0000-0002-6445-0743
Gdańsk University of Technology · PL

Funding

Narodowym Centrum Nauki 2017/26/D/NZ1/00497
6 · The paper itself

Abstract

The biology and chemistry of proteins and peptides are inextricably linked with water as the solvent. The reason for the high stability of some proteins or uncontrolled aggregation of others may be hidden in the properties of their hydration water. In this study, we investigated the effect of stabilizing osmolyte-TMAO (trimethylamine

Indexed as

Chemical PhenomenaGlycineGlycylglycineMethylaminesMolecular Dynamics SimulationOsmotic PressurePeptidesSolutionsSpectroscopy, Fourier Transform InfraredUreaWaterGlycineGlycylglycineMethylaminesPeptidesSolutionstrimethyloxamineUreaWaterFTIR spectroscopyhydration waterMD simulationsmolecular chaperonesosmolytesprotein foldingprotein misfoldingsmall molecules

Identifiers

PMID34502252
PMCPMC8431001
OpenAlexW3196721521

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.