Evidence map›Paper›PMID 34502169›Full record

ArticleInternational journal of molecular sciences2021

Unraveling the Relevance of ARL GTPases in Cutaneous Melanoma Prognosis through Integrated Bioinformatics Analysis.

Cheila Brito, Bruno Costa-Silva, Duarte C Barral, Marta Pojo

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Quantitative Proteomic Analysis of Macrophages Infected withInternational journal of molecular sciences · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Recent Trends in Cancer Genomics and Bioinformatics Tools Development.International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Cheila BritoUnidade de Investigação em Patobiologia Molecular (UIPM) do Instituto Português de Oncologia de Lisboa Francisco Gentil E.P.E., Rua Prof. Lima Basto, 1099-023 Lisbon, Portugal.
Bruno Costa-SilvaChampalimaud Research, Champalimaud Centre for the Unknown, Avenida de Brasília, 1400-038 Lisbon, Portugal.ORCID 0000-0002-5932-6211
Duarte C BarraliNOVA4Health, CEDOC, NOVA Medical School, NMS, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal.ORCID 0000-0001-8867-2407
Marta PojoUnidade de Investigação em Patobiologia Molecular (UIPM) do Instituto Português de Oncologia de Lisboa Francisco Gentil E.P.E., Rua Prof. Lima Basto, 1099-023 Lisbon, Portugal.
Champalimaud Foundation · PTUniversidade Nova de Lisboa · PT

Funding

iNOVA4Health UIDB/04462/2020Liga Portuguesa Contra o Cancro - Núcleo Regional do Sul LPCC-NRS
6 · The paper itself

Abstract

Cutaneous melanoma (CM) is the deadliest skin cancer, whose molecular pathways underlying its malignancy remain unclear. Therefore, new information to guide evidence-based clinical decisions is required. Adenosine diphosphate (ADP)-ribosylation factor-like (ARL) proteins are membrane trafficking regulators whose biological relevance in CM is undetermined. Here, we investigated

Indexed as

Computational BiologyDisease SusceptibilityADP-Ribosylation FactorsAnimalsBiomarkers, TumorCell CommunicationCutaneous Malignant MelanomaEpigenesis, GeneticGene Expression Regulation, NeoplasticGene Regulatory NetworksHumansMelanomaMembrane ProteinsNeoplasm MetastasisNeoplasm StagingPromoter Regions, GeneticADP-ribosylation factor related proteinsADP-Ribosylation FactorsBiomarkers, TumorMembrane ProteinsADP-ribosylation factor-like (ARL)biomarkerscutaneous melanomaimmune microenvironmentin silico studymetastasisprognosissmall GTPases

Identifiers

PMID34502169
PMCPMC8431576
OpenAlexW3198098198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.