Evidence map›Paper›PMID 34502166›Full record

ReviewInternational journal of molecular sciences2021

Integrated Medicine for Chemotherapy-Induced Peripheral Neuropathy.

Chih-Hung Tsai, Yuan-Ho Lin, Yung-Sheng Li, Trung-Loc Ho, Le Huynh Hoai Thuong, Yu-Huei Liu

Registry-linked trialAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05904340 (The Efficacy of Social Media Assisted Home-based Transcutaneous Electrical Acupoint Stimulation on Symptoms Associated with Chemotherapy Induced Peripheral Neuropathy in Patients with Breast Cancer), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05904340 narecruitingnot on this mapstarted 2023, after this paper: background citation

The Efficacy of Social Media Assisted Home-based Transcutaneous Electrical Acupoint Stimulation on Symptoms Associated with Chemotherapy Induced Peripheral Neuropathy in Patients with Breast Cancer

TypeinterventionalSponsorNational Taipei University of Nursing and Health SciencesRan2023 to 2025Enrolled86ConditionsBreast Neoplasms, Chemotherapy-induced Peripheral NeuropathyArmsTranscutaneous Electrical Nerve Stimulation
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Activation of µ-δ Opioid Receptor Heteromer Attenuates Chemotherapy-Induced Neuropathic Pain in Mice.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025
    Article
  4. Core symptoms in patients with colorectal cancer receiving chemotherapy: a network analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Chemotherapy-induced polyneuropathy in cancer care-the patient perspective.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  10. New Advancements in Cisplatin-Based Treatments.International journal of molecular sciences · 2023
    Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chih-Hung TsaiGraduate Institute of Integrated Medicine, China Medical University, Taichung 40402, Taiwan.ORCID 0000-0002-8459-0348
Yuan-Ho LinGraduate Institute of Integrated Medicine, China Medical University, Taichung 40402, Taiwan.ORCID 0000-0003-1950-5845
Yung-Sheng LiGraduate Institute of Integrated Medicine, China Medical University, Taichung 40402, Taiwan.ORCID 0000-0001-7867-2120
Trung-Loc HoInternational Master's Program of Biomedical Sciences, China Medical University, Taichun 40402, Taiwan.
Le Huynh Hoai ThuongInternational Master's Program of Biomedical Sciences, China Medical University, Taichun 40402, Taiwan.
Yu-Huei LiuGraduate Institute of Integrated Medicine, China Medical University, Taichung 40402, Taiwan.

Funding

Ministry of Education 10971701Ministry of Education the Drug Development Center, China Medical University, under the Featured Areas Research Center Program within the framework of the Higher Education Sprout ProjectMinistry of Science and Technology, Taiwan MOST 107-2320-B-039-032-MY3
6 · The paper itself

Abstract

Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of typical chemotherapeutics among cancer survivors. Despite the recent progress, the effective prevention and treatment strategies for CIPN remain limited. Better understanding of the pathogenesis of CIPN may provide new niches for developing a new ideal therapeutic strategy. This review summarizes the current understanding of CIPN and current recommendations along with completed/active clinical trials and aims to foster translational research to improve the development of effective strategies for managing CIPN.

Indexed as

Disease SusceptibilityIntegrative MedicineAntineoplastic AgentsClinical Trials as TopicCombined Modality TherapyDisease ManagementDrug-Related Side Effects and Adverse ReactionsHumansPeripheral Nervous System DiseasesTreatment OutcomeAntineoplastic Agentsalternative and complimentary medicinescancer survivorschemotherapy-induced peripheral neuropathynew drug development

Identifiers

PMID34502166
PMCPMC8430591

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.